objective: pulmonary air-leakage especially pneumothorax (ptx), is a severe complication in neonates. the aim of this study was to assess the predisposing factors and frequency of ptx among the low birth weight (lbw) premature infants, under mechanical ventilation. methods: this cross sectional study was performed in 121 lbw intubated premature infants at neonatal intensive care unit of a child...

Objective: Most   neonates admitted to neonatal wards do not tolerate sufficient milk.  Recently the effect of erythromycin on increasing feeding tolerance in neonates has been studied. In this study the effectiveness of oral, high dose Erythromycin a prokinetic agent was used to enhance feeding tolerance in these neonates.  Methods: This prospective randomized controlled clinical trial was con...

BACKGROUND Hospitalized premature babies often undergo various painful procedures. Kangaroo mother care (KMC) and swaddling are two pain reduction methods. OBJECTIVES This study was undertaken to compare the effects of swaddling and KMC on pain during venous sampling in premature neonates. PATIENTS AND METHODS This study was performed as a randomized clinical trial on 90 premature neonates....

Coagulase-negative staphylococci (C-NS) are a frequent cause of bacteraemia in premature neonates. It is likely that the strains of C-NS causing bacterial sepsis in premature neonates have their origin on the patient's skin surface. We have studied the quantitative development of the skin microflora at eight sites on premature neonates. A swab wash method was used to sample and enumerate the cu...

Background: Respiratory distress syndrome is one of the main complications associated with low birth weight, and a main cause of mortality in premature neonates. The present study aimed to compare the efficacy of ventilator continuous positive airway pressure (CPAP) and bubble CPAP in the treatment of respiratory distress syndrome (RDS) in premature neonates. Methods: This randomized controlled...

objective: preterm infants are prone to intraventricular hemorrhage. they may suffer from significant morbidity and mortality particularly in those with high-grade hemorrhage. our objective was to determine the incidence of intraventricular hemorrhage in premature infants transported to a tertiary center compared with those delivered at the level iii facility.  methods: we evaluated all prematu...

background :severe neonatal hyperbilirubinemia is associated with significant morbidity and mortality. this study was conducted to investigate the causes of severe hyperbilirubinemia leading to exchange transfusion (et) from march 2009 to march 2011 in bahrami children hospital, tehran, iran in order to establish guidelines to prevent profound jaundice & et.   methods : 94 neonates underwent et...

BACKGROUND Patent ductus arteriosus is a common congenital cardiac condition. Its importance is mostly underestimated and accepted as an "easy" heart disease. Physiological consequences of pulmonary overflow may cause severe mortality in premature neonates. Accurate timing of surgical intervention is essential to decrease the mortality in very low birth weight premature infants. On-site surgery...

BACKGROUND Factors influencing the oral flora of premature infants have not been adequately investigated. OBJECTIVE To investigate the effects of gestational age and of anti-bacterial therapy on the oral flora of premature infants. METHODS Oral cultures were obtained at age 1 day and age 10 days from 65 premature infants, divided into three groups: a) 24 neonates of 30-34 weeks gestation wh...

INTRODUCTION Treatment of infections in neonates with gentamicin is a balance between optimising bactericidal effect and minimising adverse effects. Previously, at the Neonatal Intensive Care Unit (NICU) at Kolding Hospital, Denmark, neonates suspected of having infections were treated daily with gentamicin 5 mg/kg for the first three days, thus exposing the smallest neonates to double gentamic...