Promotion and protection of breastfeeding is an important strategy in prevention of Vitamin A (Retinol) deficiency in childhood. Breast milk retinol’s allows us the chance to reach the maternal nutritional status and go over infant status. This study aimed to know the retinol and fat content in mature breast milk from Novo Cruzeiro’s population, Brazil. It was analyzes 63 samples of breast milk...

BACKGROUND Because of the central functions of the mitochondria in providing metabolic energy and initiating apoptosis on one hand and the role that microRNA (miRNA) play in gene expression, we hypothesized that some miRNA could be present in the mitochondria for post-transcriptomic regulation by RNA interference. We intend to identify miRNA localized in the mitochondria isolated from human ske...

Situations including premature infants, or those in which there is a rejection to breastfeeding, require the use infant formulas for total or partial replacement of human milk. The objective of this study was to determine the lipid content and to identify the lipid profile of infant formulas. Samples were collected from ten different infant formulas, used as a substitute for breast milk at the ...

Comparison of cytohormonal patterns in full-term and pre-term babies of both sexes showed significant differences. At birth, irrespective of gestational age, both groups had high oestrogen levels, reflecting the maternal hormonal environment, but whereas the mature neonates were capable of metabolising and excreting the excess hormone within the first week of life, the pre-term infants took muc...

MicroRNAs (miRNAs) constitute an important class of small regulatory RNAs that are derived from distinct hairpin precursors (pre-miRNAs). In contrast to mature miRNAs, which have been characterized in numerous genome-wide studies of different organisms, research on global profiling of pre-miRNAs is limited. Here, using massive parallel sequencing, we have performed global characterization of bo...

At birth the newborn infant is required to make an abrupt adjustment to a new environment. Hitherto its existence has been parasitic and its needs have been supplied by the maternal organism. The most immediate dramatic changes required to support extra uterine life are concerned with respiration and the circulation. The infant must achieve a regular respiratory rhythm and be able to expand its...

Seizures in a term infant with Ohtahara syndrome, associated with polymicrogyria, and a pre-term neonate with similar clinical features, failed to respond to conventional anticonvulsants, but were controlled with vigabatrin monotherapy. Another infant with Aicardi syndrome improved with vigabatrin. Autopsy in the first infant showed no evidence of intramyelinic oedema. The developmental outcome...

At birth the newborn infant is required to make an abrupt adjustment to a new environment. Hitherto its existence has been parasitic and its needs have been supplied by the maternal organism. The most immediate dramatic changes required to support extra uterine life are concerned with respiration and the circulation. The infant must achieve a regular respiratory rhythm and be able to expand its...