Background: The therapeu c administra on of I for thyroid remnant abla on and for metastases comes up with some adverse effects. This study was conducted to inves gate whether single high dose radioiodine therapy affects lacrimal gland func ons or not. Materials and Methods: Seventy‐eight eyes of 39 pa ents, who were diagnosed as differen ated thyroid carcinoma, were objec vely tested with Schi...

Dear Editor, Two cases with epiphora and medial canthal mass showed a cyst within the lacrimal sac that compressed the lacrimal drainage system. We describe a new lacrimal sac anomaly of lacrimal intrasaccal cyst, which has not yet been reported. A 31-year-old woman was referred for epiphora in her left eye for 17 years. She also presented with a 10-year history of a palpable mass below the med...

THE USUAL approach to the lacrimal sac and the area around is through the standard curved incision, with the centre of the concavity about 2-3 mm. from the inner margin of the inner canthus. It can be termed "adequate", although, to get a good view and to have freedom of manoeuvre, the incision has often to be widely stretched in all directions. Even then, one is often working in a fairly deep ...

The lacrimal system is comprised of the lacrimal glands for tear production and the lacrimal drainage system for draining tears away from the eyes. Congenital lacrimal system anomalies other than nasolacrimal duct obstruction are uncommon. Congenital lacrimal fistulae are a rare developmental anomaly, and when they occur, they are usually unilateral. Fistulae and diverticulae can originate from...

Sjögren's syndrome (SjS) is a systemic autoimmune disease in which an immunological attack against the salivary and lacrimal glands results, respectively, in severe dry mouth and dry eye diseases. Although a CD4+ T lymphocyte population is an integral component in the pathogenesis of SjS, recent studies have focused on the importance the B lymphocyte plays in both the pre-clinical and clinical ...

OBJECTIVE To observe the treatment outcomes of a crescent-shaped conjunctiva resection combined with conjunctiva sclera fixation for severe conjunctivochalasis. PATIENTS AND METHODS Eleven (22 eyes) patients with severe conjunctivochalasis were enrolled in this study. They consented to undergo crescent-shaped conjunctiva resection and conjunctiva sclera fixation, to evaluate their symptoms an...

BACKGROUND Study of human lacrimal cell biology is limited by poor access to tissue samples, heterogeneous cell composition of tissue and a lack of established lacrimal epithelial markers. In order to further our understanding of lacrimal cell biology, we sought to find a better marker for human lacrimal epithelial cells, compared to what has been reported in the literature. METHODS We utiliz...

BACKGROUND The study of human lacrimal gland biology and development is limited. Lacrimal gland tissue is damaged or poorly functional in a number of disease states including dry eye disease. Development of cell based therapies for lacrimal gland diseases requires a better understanding of the gene expression and signaling pathways in lacrimal gland. Differential gene expression analysis betwee...

Corneal hydration and protection can be achieved through increased lubrication or decreased evaporation. Hence, an important therapeutic strategy to corneal desiccation involves occlusion of the lacrimal drainage system in order to decrease tear outflow and provide additional ocular surface hydration. Three general approaches can be used: temporary, reversible, or permanent occlusion of the lac...

Adenoid cystic carcinoma (ACC), is one of the most common primary malignant tumors of the lacrimal gland. It accounts for less than 4% of all lacrimal gland tumours. Mean age of incidence is 40 years 1 . It has a poor prognosis, in view of its locally invasive and metastatic potential .2-7 . Radical Excision with negative margin is the treatment of choice. However, the complex anatomy of orbita...