Paraquat (PQ) is an herbicide used extensively in agriculture. This agent is also suspected to be a risk factor for Parkinson's disease (PD) by harming nigro-striatal dopamine neurons. There is likely, genetic-based, individual variability in susceptibility to PQ neurotoxicity related PD. In this study, we measured the delivery of PQ to the brain after three weekly injections of PQ at 5 mg kg(-...

The previous mapping lecture demonstrated how, in the absence of errors, STS mapping could be solved efficiently via a reduction to a well-known abstract problem called the consecutive-ones problem. The solution made use of a data structure called a PQ-tree which eloquently represents all possible orderings of the STS sites that are consistent with the data. The flaw in this approach, however, ...

background: paraquat (pq) poisoning is highly fatal; and therefore, clinicians should be familiar with prompt approach to and poor prognostic features of this type of poisoning. hence, in this study, clinical profile, management and outcome of a series of patients with pq poisoning are presented. methods: a retrospective review of medical records of patients poisoned with pq who were treated at...

single phase diode clamped multilevel inverter Department of.This paper presents a single phase multilevel inverter for using as a voltage harmonic source. First, a single phase multilevel inverter system is presented and.The structure of the multilevel inverter using cascaded-inverters with separated dc. single phase multilevel inverter 5 Single-phase configuration of an m-level cascaded inver...

Paraquat (PQ) has been demonstrated that the main target organ for the toxicity is the lung. This study aimed to investigate the potential protective effect of PDTC on the PQ-induced pulmonary damage. Fifty-four rats were divided into control, PQ-treated and PQ+PDTC-treated groups. Rats in the PQ group were administrated 40 mg/kg PQ by gastric gavage, and PDTC group with 40 mg/kg PQ followed by...

In this paper we present a method (linear in the size of the formal context) to solve the seriation problem for formal contexts. We show that any maximal solution can be represented by a PQ-Tree. Moreover, the set of PQ-Trees can be seen as a distributive lattice. This lattice yields a consensus method which deals with the multiple solutions.

This cytogenetic and pharmacological study attempts to clarify genotoxicity-enhancement-effect of dl-α-tocopherol (one form of vitamin E) in combination with the herbicide 1,1'-dimetyl-4,4'-bipyridium dichloride (paraquat, PQ) on cultured anuran leukocytes using the superoxide dismutase-mimic Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin (Mn(III)TMpyP), the hydrogen peroxide-scavenger catalase a...

Hematotoxicity in individuals genetically deficient in glucose-6-phosphate 22 dehydrogenase (G6PD) activity is the major limitation of primaquine (PQ), the only antimalarial 23 drug in clinical use for treatment of relapsing P. vivax malaria. PQ is currently clinically used in 24 its racemic form. A scalable procedure was developed to resolve racemic PQ thus providing pure 25 enantiomers for th...

since it is essential to deliver smoothed sinusoidal voltage to the customers, diagnosing power quality (pq) events has played important role in power delivery and conversion. this diagnostic scheme should be accurate to classify pq events from other events in power system. also it should be fast enough to rapidly mitigate pq events. in this paper, an algorithm based on core vector machine (cvm...