Paraquat is a commonly used herbicide in many countries which can lead to systematic poisoning on exposure, In this study, paraquat (PQ)-induced changes in the expression of Cyclooxygenase-2 (COX-2) along with biochemical and histopathological changes in the lungs, liver and kidneys were studied. Twenty four male Wistar rats (180-200 g) were exposed either against saline as control group or var...

Background: Paraquat (PQ) is one of the most important herbicides used in agriculture. Objectives: This study was conducted to compare preventive effect vitamin D (Vit D) and N-acetylcysteine (NAC) against kidney injury rats versus promotive PQ. Methods: In this study, were divided into six groups. The control group (group 1) received normal saline, Vit 2) intraperitoneal (IP) injections of+Vit...

Paraquat (PQ)-induced pulmonary toxicity is known to result in pulmonary edema, infiltration of inflammatory cells and damage to the alveolar epithelium, which may progress to severe fibrosis. Matrix metalloproteinases (MMPs) and their physiological inhibitors, tissue inhibitors of matrix metalloproteinases (TIMPs), which degrade and remodel the excess extracellular matrix, are believed to play...

Wind farms can affect the power quality (PQ) of the power supply grid, with subsequent impacts on the safe and stable operation of other electrical equipment. A novel PQ prediction, early warning, and control approach for the common coupling points between wind farms and the network is proposed in this paper. We then quantify PQ problems and provide rational support measures. To obtain predicte...

Objective: Interleukin-17A (IL-17A) is a potent proinflammatory factor. Our study aimed to investigate the role of IL-17A on acute lung injury (ALI) induced by paraquat (PQ) and the potential way. Methods: A total of 180 female mice were randomly and evenly divided into 9 groups: Control group (NS), PQ groups (4 groups) and PQ+A b groups (4 groups). NS group mice were treated with equal volume ...

Rats exposed to the quaternary herbicide paraquat (PQ) exhibit oxidative stress and lung irijury.'In the present study, we investigated the effect ofmultiple exposures to PQ on aerobic perfbrmance during progressive exercise on a treadmiU in rats. PQ was dissolved in saline (SAL) (1O mgfml) and administered intraperitoneally 7 mglkg body wt to Wistar rats (n = 5) once a week for one month, Cont...

Pulmonary fibrosis is one of the most common complications of paraquat (PQ) poisoning, which demands for more effective therapies. Accumulating evidence suggests adiponectin (APN) may be a promising therapy against fibrotic diseases. In the current study, we determine whether the exogenous globular APN isoform protects against pulmonary fibrosis in PQ-treated mice and human lung fibroblasts, an...

Power Quality (PQ) parameters such as voltage RMS value, Total Harmonic Distortion (THD), and Power Factor (PF) are main topics to be considered in the connection of sensitive loads to the grid. In this paper, a Unified Power Quality Conditioner (UPQC) based on an Indirect Matrix Converter (IMC) is proposed to address some PQ issues as mitigation of voltage harmonics and compensation of sags an...

The use of the herbicide paraquat (1,1'-dimethyl-4,4'-bipyridylium dichloride; PQ) which is widely used in agriculture is known to cause dopaminergic neurotoxicity. However, the mechanisms underlying this effect are not fully understood. This present study investigated the behavioral manifestations, motor coordination, and dopaminergic neurodegeneration following exposure to PQ. Male rats were ...

Paraquat (PQ) is a dopaminergic neurotoxin and a well-known pneumotoxicant that exerts its toxic effect via oxidative stress-mediated cellular injuries. This study investigated the protective effects of Tualang honey against PQ-induced toxicity in the midbrain and lungs of rats. The rats were orally treated with distilled water (2 mL/kg/day), Tualang honey (1.0 g/kg/day), or ubiquinol (0.2 g/kg...