Introduction: Primary open angle glaucoma is a symptom complex wherein there is damage to the optic nerve head with characteristic morphological and functional alterations in Optic Nerve Head (ONH). Aim: To compare the recent surgical approach minitrab with conventional trabeculectomy with reference to post-operative success. Materials and Methods: This prospective study was done in Theni Medic...

Objective: To compare the success rate of trabeculectomy with and without Mitomycin C in lowering intraocular pressure. Design: Prospective, comparative, randomized, interventional study. Duration: Two years. Place: Department of Ophthalmology, Lady Reading Hospital, Peshawar. Material and Methods :This prospective study of 100 eyes of 80 patients of glaucoma was conducted from January 2005 to ...

BACKGROUND Antifibrotic agents are commonly utilized to enhance the success rates of trabeculectomy. Novel approaches to further improve success rates and reduce the risks of complications are needed. The purpose of this study was to compare intraocular pressure (IOP)-lowering efficacy and safety of trabeculectomy or combined phacoemulsification and trabeculectomy with mitomycin-C (MMC) vs. Col...

PURPOSE To compare the efficacy and safety of repeat and initial trabeculectomy with mitomycine C (MMC). METHODS Eighty seven patients, who had underwent repeat (repeat group) or initial (initial group) trabeculectomy with MMC, were enrolled in this prospective trial. Postoperative outcome measures included the amount of decrease in intraocular pressure (IOP), the number of anti-glaucoma medi...

This study compares long-term efficacy (up to 48 months) of cyclocryocoagulation and trabeculectomy in lowering the intraocular pressure (IOP). Intraocular pressure evolution after cyclocryocoagulation in one eye and trabeculectomy in the fellow eye for the treatment of primary open- and narrow-angle glaucoma was monitored in five patients. After 4 years both interventions were still active. Cy...

Trabeculectomy, despite producing an effective reduction in intraocular pressure, may not prevent continued visual field loss. This may be because of the presence of other factors in the pathogenesis of glaucoma. Vascular factors have been suggested as being particularly important. To study the effect of trabeculectomy on ocular blood flow the technique of ocular pulse analysis has been used to...

AIM To compare the long term mean intraocular pressure (IOP) reduction after non-augmented single site phacotrabeculectomy with that after trabeculectomy and to determine the relation between preoperative IOP and IOP reduction. METHODS A group of 44 consecutive patients with chronic open angle glaucoma who underwent phacotrabeculectomy were matched to a trabeculectomy control group and the re...

The success of trabeculectomy, which is considered the gold standard in the surgical treatment of glaucoma, depends on the wound healing response. The introduction of antiproliferative agents such as mitomycin C (MMC) has increased the success rates of trabeculectomy. However, complications due to these agents can be challenging to manage. Hence, it is important to determine the most efficaciou...

Sturge-Weber syndrome (SWS) is a rare congenital neurocutaneous disorder that causes congenital glaucoma. Previous experiences have shown that drainage procedures are often required to control associated glaucoma. The conventional surgical approach in trabeculectomy carries a significant risk of intraoperative expulsive hemorrhage. Here, we describe a modified approach of the conventional trabe...

OBJECTIVE To evaluate the efficacy and safety of Ex-PRESS implantation (Ex-PRESS) compared to trabeculectomy in the treatment of patients with open-angle glaucoma (OAG). METHODS A comprehensive literature search using the Cochrane Methodology Register to identify randomized controlled clinical trials (RCCTs) comparing Ex-PRESS to trabeculectomy in patients with OAG. Efficacy estimates were me...