2- methylsulfonyl - 5- (1-methyl-5-nitro- 2 – imidazolyl ) 1,3,4 - thiadiazole ( 1 ) was prepared by twa independent routes.1) reaction of 1-methyl-2-formyl-5- nitroimidazole (3) with methyl hydrazinecarbodithioate gave the hydrazone 4. reaction of compound 4 with acetic anhydride followed by potassium permanganate oxidation of the intermediate 5 gave the desired compound 1. 2) reaction of thio...

A 19-year-old woman was referred to our emergency department for massive vaginal hemorrhage following an attempted clandestine abortion by intravaginal instillation of potassium permanganate crystals. Primigravida, she 7 weeks pregnant and had no particular pathological history. Upon admission, in hemorrhagic shock with blood pressure at 7/3 mmHg tachycardia 152 bpm. Pelvic examination revealed...

Dear Editor-in-Chief, We read with great interest the article entitled “A review of aluminium phosphide poisoning and a flowchart to treat it” written by Hashemi-Domeneh et al. (1) and recently published in the Archives of Industrial Hygiene and Toxicology. The authors mentioned performing a gastric lavage using a solution of potassium permanganate (1/10000/1 g per 10 L) and administering activ...