Nine hydrated complexes of Group 2 (alkaline earth) cations with organic ligands which are N-substituted amino acids containing the 6-amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl group have been structurally characterized. The octahydrated calcium glycinate complex, where the six-coordinate Ca cation lies on an inversion centre in the space group P(-)1, forms a finite (zero-dimensio...

atp-sensitive potassium (katp) channel openers have a relaxation effect due to the lower cellular membrane potential and inhibit calcium influx. there has been considerable interest in exploring katp channel openers in the treatment of various diseases such as cardiovascular, cerebrovascular, and urinary system disease and premature labor. the purpose of this study was to synthesize 3,3,6,6-tet...

Utilization of ionic liquids (ILs) for carbon dioxide (CO2) capture is continuously growing, and further understanding the factors that influence its solubility (notably new ILs) crucial. Herein, CO2 absorption two 1,2,4-triazolium-based ILs was compared with imidazolium-based Ils different anions, namely bis(trifluoromethylsulfonyl)imide, tetrafluoroborate, glycinate. The capacity determined u...

In this study, a physical characterization (density ( ρ ), refractive index n D speed of sound u ) and dynamic viscosity η )) as function temperature (298.15–343.15 K) choline glycinate (ChGly) its binary mixtures with water or/and methanol over the entire composition range was performed from 298.15 K to 323.15 K. Several derived properties pure ionic liquid excess molar volume V m E changes on...

The aim of this study was to investigate the pharmacokinetics of thiamphenicol glycinate (TG) and thiamphenicol (TAP) after intravenous (i.v.) infusion of TG hydrochloride in healthy Chinese by evaluating the pharmacokinetic parameters, to provide clinical guidance in TG application. In this double-blinded, phase I clinical trial, 24 healthy Chinese volunteers were recruited and divided into th...