BACKGROUND Exposure to chromium during electroplating is a recognised though poorly characterised cause of occupational asthma. The first series of such patients referred to a specialist occupational lung disease clinic is reported. METHODS The diagnosis of occupational asthma was made from a history of asthma with rest day improvement and confirmed by specific bronchial provocation testing w...

objective: hexavalent chromium [cr (vi)] compounds are well-known environmental contaminants  generated from industrial processes. several studies have reported the harmful effects of cr (vi) on different organs, however, little is known about neurotoxic effects of cr (vi). the aim of this study is to investigate the toxic effects of cr (vi) on pc12 cells. methods: pc12 cells were cultured foll...

BACKGROUND Construction workers have a substantial risk of developing irritant and/or allergic contact dermatitis. Unfortunately, however, there is little population-based epidemiological data relating to occupational skin diseases (OSD) in the European construction industry that allow assessment of preventive measures. OBJECTIVES In this investigation, the yearly incidence rates and causes o...

We optimized proton-induced X-ray emission (PIXE) for tissue analysis in a toxicity-disposition study. We used cultured rabbit renal slices as the biological system to demonstrate the use of PIXE analysis. The renal slices were exposed to HgCl2, CdCl2, K2Cr2O7, or NaAsO2 alone or in a mixture. The PIXE analysis provides information on concentrations of elements above atomic number 11, and it is...

approved:_____________________________________________________ Tyler Radniecki Incompatibility between Fenton’s Reagents and a potassium dichromate COD test provides interference that prevent accurate measurements of the concentration of organics from oxidized samples. Several treatment options were tested to remove this interference. Oxidation of reagents was eliminated as a potential method f...

SEROTONIN (5-hydroxytryptamine, 5-HT) in blood is transported almost exclusively by circulating platelets.1 Early biochemical and pharmacologic studies demonstrated that most of the 5-HT was found in granules present in platelet hyaloplasm.2” Recently, several laboratories have suggested that platelet serotonin is concentrated within a specific type of platelet organelle, the dense body58 ( Fig...

Gas-chromatographic methods for ethanol quantitation provide greater specificity than traditional oxidimetric methods. The specificity of oxidimetric methods such as those of Kozelka-Hine (1) and Widmark (2) rely on the arguments that: (a) the sample came from a living person and (b) drugs or chemicals that would appreciably react with potassium dichromate could not be expected to be present in...