There are rising public health concerns about the links between consumption of sugar-sweetened beverages and weight gain, obesity, and other metabolic problems. Sodium citrate (Na-citrate) is used as an additive in colas and various commercial drinks worldwide. Although potassium citrate (K-citrate) has been prescribed and well accepted by urologists for treating urinary stone disease (urolithi...

PURPOSE Critically evaluate the experimental evidence and clinical trial outcomes as the basis for use of magnesium (Mg) supplements as therapy for calcium oxalate nephrolithiasis. MATERIALS AND METHODS Literature search of MedLine and Web of Science through January 2005; articles cited in papers found by searches. RESULTS Magnesium inhibits calcium oxalate crystallization in human urine an...

Nephrolithiasis is a common problem encountered in clinical practice. Almost 2 million outpatient visits for a primary diagnosis of nephrolithiasis were recorded in the year 2000 in the United States [1]. This condition affects approximately 5-10% of adults during their lifetime and may also affect the pediatric population. Recurrence is present in almost 50% of patients within 5 years of their...

OBJECTIVE Renal calculus disease is associated with recurrence after its surgical removal in large number of cases. Kulattha is acclaimed to have litholytic property in ayurvedic literature. We decided to compare the litholytic property of Kulattha with potassium citrate, an agent used to reduce stone recurrence in modern medicine. METHODS Forty seven patients with diagnosis of calcium oxalat...

The study was carried out to determine the in vitro effect of Plantago major extract on calcium oxalate crystals and to compare the effects of Plantago major extract with clinically used drugs like allopurinol and potassium citrate (positive controls). Modified Schneider slide gel method was used for the in vitro study and the crystals formed were measured by Image Analyser system KS 300, 3.0 C...

BACKGROUND Few treatments are available to slow the progression to renal failure in autosomal dominant polycystic kidney disease (PKD). In an animal model of PKD, the male heterozygous Han:SPRD rat, intake of a solution of potassium citrate plus citric acid (KCitr) from age one to three months prevented a decline in glomerular filtration rate (GFR). The present study tested whether this benefic...

BACKGROUND Kidney stones affect people worldwide and have a high rate of recurrence even with treatment. Recurrences are particularly prevalent in people with low urinary citrate levels. These people have a higher incidence of calcium phosphate and calcium oxalate stones. Oral citrate therapy increases the urinary citrate levels, which in turn binds with calcium and inhibits the crystallisation...

Possibility of silver nanoparticle synthesis by reduction of silver trifluoro acetate inorganic media (ethylene glycol, 2-methoxyethanol, ethyl acetate) was studied. Quercetin, ascorbicacid and potassium citrate were used asreducing agents.

A 28-year-old female with history of hypothyroidism, Sjögren's Syndrome, and Systemic Lupus Erythematosus (SLE) presented with complaints of severe generalized weakness, muscle pain, nausea, vomiting, and anorexia. Physical examination was unremarkable. Laboratory test showed hypokalemia at 1.6 mmol/l, nonanion metabolic acidosis with HCO3 of 11 mmol/l, random urine pH of 7.0, and urine anion g...

Citrate is one of the most important organic acids in many fruits and its concentration plays a critical role in organoleptic properties. The regulation of citrate accumulation throughout fruit development, and the origins of the phenotypic variability of the citrate concentration within fruit species remain to be clarified. In the present study, we developed a process-based model of citrate ac...