The purpose of this study was to quantify how shivering activity would be affected by large changes in fuel metabolism (see Haman F, Peronnet F, Kenny GP, Doucet E, Massicotte D, Lavoie C, and Weber J-M, J Appl Physiol 96: 000-000, 2004). Adult men were exposed to 10 degrees C for 2 h after a low-carbohydrate diet and exercise (Lo) and after high-carbohydrate diet without exercise (Hi). Using s...

INTRODUCTION Mild therapeutic hypothermia has been shown to improve outcome for patients after cardiac arrest and may be beneficial for ischaemic stroke and myocardial ischaemia patients. However, in the awake patient, even a small decrease of core temperature provokes vigorous autonomic reactions-vasoconstriction and shivering-which both inhibit efficient core cooling. Meperidine and skin warm...

BACKGROUND Hypothermia may be beneficial in stroke victims; however, it provokes vigorous shivering. Buspirone and dexmedetomidine each linearly reduce the shivering threshold with minimal sedation and no respiratory depression. This study tested the hypotheses that the combination of buspirone and dexmedetomidine would (1) synergistically reduce the shivering threshold, (2) synergistically red...

Kvadsheim, Petter H., Lars P. Folkow, and Arnoldus Schytte Blix. Inhibition of shivering in hypothermic seals during diving. Am J Physiol Regul Integr Comp Physiol 289: R326–R331, 2005. First published March 10, 2005; doi:10.1152/ajpregu.00708.2004.—The mammalian response to hypothermia is increased metabolic heat production, usually by way of muscular activity, such as shivering. Seals, howeve...

BACKGROUND Shivering during regional anesthesia is a common complication and is related to a decrease in the patient's core body temperature. Previous studies have shown that acupuncture on specific acupoints can preserve core body temperature. The present study evaluated the effect of electroacupuncture in preventing the shivering caused by regional anesthesia. METHODS This prospective and r...

Haman, François. Shivering in the cold: from mechanisms of fuel selection to survival. J Appl Physiol 100: 1702–1708, 2006; doi:10.1152/japplphysiol.01088.2005.—In coldexposed adult humans, significant or lethal decreases in body temperature are delayed by reducing heat loss via peripheral vasoconstriction and by increasing rates of heat production via shivering thermogenesis. This brief review...

Introduction: Shivering is a protective reaction. It increases the production of body temperature by muscular contraction. Post-surgery shivering is one of the prevalent side effects of anesthesia. This is usually accompanied with other problems such as oxygen consumption increase, intracranialpressureincrease, and other complications. Hence, this study compared the effect of various doses of k...

BACKGROUND Ondansetron, a serotonin-3 receptor antagonist, reduces postoperative shivering. Drugs that reduce shivering usually impair central thermoregulatory control, and may thus be useful for preventing shivering during induction of therapeutic hypothermia. We determined, therefore, whether ondansetron reduces the major autonomic thermoregulatory response thresholds (triggering core tempera...

Background: Shiveringis a common complication following anesthesia. Many drugs have been documented as prophylaxis of postanesthesia shivering. The aim this study was to find out better drug an antishivering agent.
 Materials and methods: This comparative carried in the Department Anesthesiology Chittagong Medical College Hospital over period 6 months starting from November 2015 April 2016...