In this article we explore the testing of non-inferiority and equivalence hypotheses arising from multiple centers when the assumption of normality is violated. In a multicenter study, the trials are typically conducted at different centers which vary in terms of location, environment, demographics among others, leading to substantial amount of heterogeneity in the patient population. This unex...

Children under the age of five constitute around 7% of the total U.S. population, and represent a segment of the population that is totally dependent on others for day-to-day activities. A significant proportion of this population spends time in some form of day care arrangement while their parents are away from home. Accounting for those children during emergencies is of high priority, which r...

The captive genetic management of threatened species strives to preserve genetic diversity and avoid inbreeding to ensure populations remain available, healthy, and viable for future reintroduction. Determining and responding to the genetic status of captive populations is therefore paramount to these programs. Here, we genotyped 19 microsatellite loci for 240 captive giant pandas (Ailuropoda m...

We read with interest the recent study published in [1] regarding persistent levels of undernutrition in city like Chandigarh. The authors have concluded that the prevalence of underweight among under-five year old children remained almost stagnant in the last one decade from 51.6% (1997) to 50.4% (2007). We would like to point out that sampling frame and design of the published study pose limi...

the interactions and linkages between urban centers and peripheral settlements are increasingly recognized as key factors in the process of social, economic and environmental changes in peripheral settlements. despite this, most practices are implicitly based on a dichotomous view of population and activities in urban and peripheral area. this paper presents that how interactions between urba...

This study examined: 1) the shifting patterns of population, economy, and center gravity in each industry using regional model, 2) socioeconomic factors influencing economy population China geographic detector model. Several major findings included following: First, economic have shifted generally to southwest. The centroid model can capture changes disparities from a dynamic perspective visual...