The present work investigated the preparation of biodegradable beads with alginate polymer by ionotropic gelation method to improve the control release properties of the antibiotic rifampicin. Ionotropic gelation method was applied to prepare beads using calcium chloride (CaCl2) as cationic component and alginate as an anionic component. In this method, adding 0.5% w/v polyvinyl alcohol (PVA) t...

In current study,a hydrogel based on biocompatible polymerwas prepared. The functionalization of polyvinyl alcohol (PVA)with epichlorohydrin(ECH) to produce epichlorohydrin-g-polyvinyl alcohol (PVA/ECH) as a suitable macroinitiator for atom transfer radical polymerization (ATRP) reaction was investigated.ThenN-vinyl pyrrolidone (NVP) waspolymerized on the surface of macroinitiatorin presence of...

We studied the effect of titanium dioxide (TiO2)nanoparticles (NPs)on ion conductivity Na+ ion-conducting nanocomposite solid polymer electrolyte (NCSPE) composed polymers poly(ethylene oxide) (PEO) and polyvinyl pyrrolidone (PVP), sodium metaperiodate (NaIO4)at concentration 10 wt%, with added TiO2NPs average size ∼ nm at from 1 wt% to 5 wt%. The electrical response thin films (150μm) PEO/PVP/...

PURPOSE To determine if the use of pigments or adding polyvinyl pyrrolidone during the fabrication of 1-DAY ACUVUE DEFINE (AD) brand contact lenses impacts open-eye corneal swelling compared with no lens wear (NLW). METHODS A partial double-masked, randomized, bilateral crossover study was conducted in 24 Asian subjects using AD, 1-DAY ACUVUE DEFINE with Lacreon (ADL), NLW, and a control lens...

PURPOSE The purpose of our study was to investigate the cellular accumulation, DNA cross-linking ability, and cellular toxicity of RH1 (2,5-diaziridinyl-3-[hydroxymethyl[-6-methyl-1,4-benzoquinone), a novel DNA alkylating agent currently in clinical trials. In addition, the in vivo efficacy of RH1 formulated in different vehicles was also compared. EXPERIMENTAL DESIGN RH1 is activated by the ...

We investigated the physical properties and tooth-whitening effect of polymeric compositions based on orally acceptable polymers, polyvinyl acetate (PVAc), ethyl cellulose (EC), pyrrolidone. The composition was prepared with hydrogen peroxide (H2O2) as a tooth-bleaching agent an polymer through simple mixing stirring in alcohol. PVAc EC polymers showed non-erosive features sustainable matrices ...