in view of the fundamental role of genetics in development of obesity, the present study aimed to investigate the single nucleotide polymorphism of some obesity-related genes among a subset of obese women living in tabriz, iran. for this purpose, 70 eligible obese women (aged 18-45 years) were genotyped for the uncoupling protein-1 (ucp-1) -3826a>g, ß3-adrenergic receptor (ß3adr) trp64arg, lept...

Background Malignant mesothelioma is a rare cancer with poor outcome, associated with asbestos exposure. Reactive oxygen species may play an important role in the mechanism of carcinogenesis; therefore, genetic variability in antioxidative defence may modify an individual's susceptibility to this cancer. This study investigated the influence of functional polymorphisms of NQO1, CAT, SOD2 and hO...

In this report, β-tubulin gene polymorphism was investigated in Haemonchus contortus  populations isolated from sheep flocks in different regions of Khouzestan province, southwestern Iran. The samples were chosen on the basis of regional variation in benzimidazole treatment background of sheep flocks. Our objective was to study the relationship between treatment background andβ -tubulin gene po...

trichosanthes kirilowii, an important economic plant in china, is sensitive to chilling. to investigate the effect of abscisic acid (aba) treatment on the chilling tolerance of trichosanthes kirilowii maxim, different concentrations of aba were sprayed on trichosanthes kirilowii leaves and the resulting catalase (cat) and superoxide dismutase (sod) activities and the malondialdehyde (mda) conte...

Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...

BACKGROUND Bronchial asthma is an inflammatory disease resulting from a combination of genetic and environmental factors. Single nucleotide polymorphisms in the regulatory regions of cytokine and antioxidant enzyme genes may affect cytokine production and enzyme activity, and thus play a contributory role in asthma pathogenesis. OBJECTIVES The aim of this study was to examine the association ...

background: cells have complex network of antioxidant enzymes that protect cells from induced damages by reactive oxygen species (ros). catalase and superoxide dismutase are known for their role as primary protection against oxidative stress. oxidative damage is an important risk factor in age-related macular degeneration disease (amd). for the first time in this study the impact of genetic pol...

The objective of this study was to search for single nucleotide polymorphism (SNP)-type polymorphisms in the dopamine D1 receptor in West Azerbaijani native chicken and look for their association with egg production and body weight traits of chickens by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP). For this purpose 180 blood samples were taken from nativ...