A neutral-detergent-solubilized-enzyme preparation derived from Phaseolus aureus hypocotyls contains two types of glycosyltransferase activity. One, mannosyltransferase enzyme activity, utilizes GDP-alpha-d-mannose as the sugar nucleotide substrate. The other, glucosyltransferase enzyme activity, utilizes GDP-alpha-d-glucose as the sugar nucleotide substrate. The soluble enzyme preparation cata...

We report a simple photolithographic approach for the creation and micropatterning of chemical functionality on polymer surfaces by use of surface-active block copolymers that contain protected photoactive functional groups. The block copolymers self-assemble at the substrate-air interface to generate a surface that is initially hydrophobic with low surface tension but that can be rendered hydr...

Topographical and biochemical characteristics of the substrate are critical for neuronal differentiation including axonal outgrowth and regeneration of neural circuits in vivo. Contact stimuli and signaling molecules allow neurons to develop and stabilize synaptic contacts. Here we present the development, characterization and functional validation of a new polymeric support able to induce neur...

bstract Solid lubricating coatings comprise a large segment of tribological materials and under a spherical contact the coating/substrate interface xperiences cyclic shear stress that leads to delamination of the coatings from the substrate and premature failure. The polymeric solid lubricating oating used in this study is an expanded PTFE/epoxy composite. The coatings experience cumulative dam...

We present an analysis of heterogeneous dynamics in molecular dynamics simulations of a polymeric film supported by an absorbing surface. Using a bead-spring model for polymers, we show that slow, immobile beads occur throughout the film, with the probability of their occurrence decreasing with distance from the substrate. Still, enough immobile beads are located near the free surface to cause ...

Implant materials need to be highly biocompatible to avoid inflammation in clinical practice. Although biodegradable polymeric implants can eliminate the need for a second surgical intervention to remove the implant materials, they may produce acidic degradation products in vivo and cause non-bacterial inflammation. Here we show the strategy of "substrate-anchored and degradation-sensitive coat...