to assess the relative contribution of genetic and environmental factors (particularly androgens) on circulating levels of lipid fractions, serum androgen and lipid fractions were measured in 34 pairs of female-female twins aged from 15- 45 years, some of whom were discordant for polycystic ovary syndrome (pcos) diagnosed by ultrasound. nineteen pairs were monozygotic twins (mz) and 15 pairs we...

OBJECTIVE Idiopathic hirsutism (IH) or polycystic ovary syndrome (PCOS) are the most common causes of hirsutism which affects 5-10% of all women. The aim of this study was to evaluate the efficacy of flutamide plus diane 35 in the treatment of idiopathic hirsutism and polycystic ovary syndrome. MATERIALS AND METHODS 26 polycystic ovary syndrome and 24 idiopathic hirsutism patients were evalua...

OBJECTIVES We aimed to investigate whether glucocorticoid receptor gene polymorphisms are associated with clinical and metabolic profiles in patients with polycystic ovary syndrome. Polycystic ovary syndrome is a complex endocrine disease that affects 5-8% of women and may be associated with metabolic syndrome, which is a risk factor for cardiovascular disease. Cortisol action and dysregulation...

Background: Meta-analysis was used to evaluate the efficacy and safety of aspirin combined with letrozole in treatment polycystic ovary syndrome (PCOS).

Objective: We examined the relationship between insulin resistance and vascular function in three insulin resistant states (type 2 diabetes mellitus, non-HIV lipodystrophic diabetes, and non-diabetic polycystic ovary syndrome (PCOS)) and in healthy controls. Research Design and Methods: The population included 12 women with type 2 diabetes, 6 with lipodystrophic diabetes, 10 with polycystic ova...

OBJECTIVES: Polycystic ovary syndrome is a heterogeneous endocrine disorder that affects reproductive-age women. The mechanisms underlying the endocrine heterogeneity and neuroendocrinology of polycystic ovary syndrome are still unclear. In this study, we investigated the expression of the kisspeptin system and gonadotropin-releasing hormone pulse regulators in the hypothalamus as well as facto...

1 Elif Karadeli1, Ayla Uckuyu2, Faika Ceylan Ciftci2, Erzat Toprak2, Erdem Turhan2, Emel Ozcimen2, Emin Alp Niron1 1Department of Radiology, 2Department of Obstetrics and Gynecology, Baskent University, Faculty of Medicine, Turkey Renal Doppler Ultrasonografi, Polikistik Over Sendromu / Renal Doppler Ultrasound, Polycystic Ovary Syndrome Polycystic Ovary Syndrome: The Correlation Between Renal ...

PCOS, features and diagnosis Polycystic ovary syndrome (PCOS) is a common reproductive endocrinological disorder among women of fertile age. The history of PCOS dates back to 1721. Sclerocystic changes were pointed out in the human ovary as early as 1844. However, the disorder was first described in 1935 by Stien & Leventhal in women who presented with amenorrhea, infertility and bilateral enla...

BACKGROUND The Canadian and American Diabetes Associations recommend the use of an oral glucose tolerance test to screen for abnormal glucose tolerance among women with polycystic ovary syndrome when their fasting plasma glucose level is 5.7 mmol/L or more (Canadian guideline) and 5.6 mmol/L or more (American). Our objective was to determine the predictive value of 5.6 mmol/L as a fasting plasm...

This guideline has been produced to provide information, based on clinical evidence, to assist clinicians with a special interest and for updating the generalist who manages women with polycystic ovary syndrome, to allow them to advise women about the long-term health consequences of the syndrome. This guideline does not cover infertility associated with polycystic ovary syndrome (PCOS), which ...