نتایج جستجو برای: polycrease ecr

تعداد نتایج: 1395  

2017
Sayoko Ito‐Harashima Mai Matsuura Masanobu Kawanishi Yoshiaki Nakagawa Takashi Yagi

Synthetic nonsteroidal ecdysone agonists, a class of insect growth regulators (IGRs), target the ecdysone receptor (EcR), which forms a heterodimer with ultraspiracle (USP) to transactivate ecdysone response genes. These compounds have high binding affinities to the EcR-USP complexes of certain insects and their toxicity is selective for certain taxonomic orders. In the present study, we develo...

Journal: :Molecular biology and evolution 2003
François Bonneton Dominique Zelus Thomas Iwema Marc Robinson-Rechavi Vincent Laudet

Ecdysteroid hormones are major regulators in reproduction and development of insects, including larval molts and metamorphosis. The functional ecdysone receptor is a heterodimer of ECR (NR1H1) and USP-RXR (NR2B4), which is the orthologue of vertebrate retinoid X receptors (RXR alpha, beta, gamma). Both proteins belong to the superfamily of nuclear hormone receptors, ligand-dependent transcripti...

Journal: :Biological chemistry 2003
Marco Grebe Sabina Przibilla Vincent C Henrich Margarethe Spindler-Barth

Mutants created by site-directed mutagenesis were used to elucidate the function of amino acids involved in ligand binding to ecdysteroid receptor (EcR) and heterodimer formation with ultraspiracle (USP). The results demonstrate the importance of the C-terminal part of the D-domain and helix 12 of EcR for hormone binding. Some amino acids are involved either in ligand binding to EcR (E476, M504...

Journal: :Developmental biology 2000
P P D'Avino C S Thummel

Drosophila imaginal discs are specified and patterned during embryonic and larval development, resulting in each cell acquiring a specific fate in the adult fly. Morphogenesis and differentiation of imaginal tissues, however, does not occur until metamorphosis, when pulses of the steroid hormone ecdysone direct these complex morphogenetic responses. In this paper, we focus on the role of ecdyso...

یکی از راه‌کارهای مهم افزایش گستره کاربرد اصلاح خواص چوب، بهرهگیری از گروه‌های عاملی فعال در ساختار چوب یا به اصطلاح آغشته ‌کردن با ترکیبات N- متیلول است. هدف از این تحقیق، بررسی ویژگی‌های فیزیکی چوب پالونیا پس از اصلاح با رزین دیواره‌ای Polycrease ECR، به‌ نام‌ دی متیلول دی هیدروکسی اتیلن‌ اوره اصلاح‌ شده (mDMDHEU) بود. نمونه‌های آزمون فیزیکی بر اساس استاندارد ASTM و EN تهیه گردیدند و به ‌روش ...

2008
Alberto A. Sagüés

This work is a preliminary examination of mechanistic issues on the comparative corrosion performance of regular epoxy-coated rebar (ECR) and dual polymer-zinc coated reinforcement (DCR) in simulated concrete pore solution with and without chloride ions, at polarizations from +100 mV to -1000 mV in the saturated calomel electrode (SCE) scale and exposure periods of 1 month or longer. Both mater...

Journal: :The Journal of Cell Biology 2004
Dimitrios Cakouros Tasman J. Daish Sharad Kumar

The steroid hormone ecdysone regulates moulting, cell death, and differentiation during insect development. Ecdysone mediates its biological effects by either direct activation of gene transcription after binding to its receptor EcR-Usp or via hierarchical transcriptional regulation of several primary transcription factors. In turn, these transcription factors regulate the expression of several...

Journal: :Development 2009
Christen K Mirth James W Truman Lynn M Riddiford

In holometabolous insects, a species-specific size, known as critical weight, needs to be reached for metamorphosis to be initiated in the absence of further nutritional input. Previously, we found that reaching critical weight depends on the insulin-dependent growth of the prothoracic glands (PGs) in Drosophila larvae. Because the PGs produce the molting hormone ecdysone, we hypothesized that ...

2015
Delphine S. Tuot Kiren Leeds Elizabeth J. Murphy Urmimala Sarkar Courtney R. Lyles Tekeshe Mekonnen Alice Hm Chen

BACKGROUND Access to specialty care remains a challenge for primary care providers and patients. Implementation of electronic referral and/or consultation (eCR) systems provides an opportunity for innovations in the delivery of specialty care. We conducted key informant interviews to identify drivers, facilitators, barriers and evaluation metrics of diverse eCR systems to inform widespread impl...

Journal: :Journal of endodontics 2016
Kreena Patel Francesco Mannocci Shanon Patel

INTRODUCTION This in vivo study assessed whether there was a difference between periapical radiographs (PRs) and cone-beam computed tomographic (CBCT) imaging in the detection, assessment, and management of external cervical resorption (ECR). The secondary aim was to determine if parallax radiographs were of any further benefit compared with a single PR. METHODS PR and CBCT data were gathered...

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