Methods A cross sectional study at the 5 year of follow-up from a JIA patients cohort, diagnosed between 2000-2008 was carried out. Treatment strategy followed the Portuguese recommendations for the treatment of JIA. The data were collected using Reuma.pt (Portuguese Register of Rheumatic Diseases). At the 5 year JADAS-27 was evaluated and used to identify patients who met the preliminary crite...

The experimental model of rheumatoid arthritis has not yet been established. Currently, two acceptable models of rheumatoid disease are being studied (Pearson, 1964), i.e. adjuvant-induced polyarthritis in rats and homologous disease (Ryzewska and Ryzewski, 1965; Ryzewski and Ryzewska, 1965). Polyarthritis appearing in rats after a subcutaneous injection of spleen cell suspension or homogenate ...

A rare triad composed of lobular panniculitis in the setting of pancreatitis and polyarthritis is termed panniculitis, pancreatitis, and polyarthritis (PPP) syndrome. Pancreatic panniculitis is a rare form of subcutaneous fat necrosis associated with underlying pancreatic disease. We describe a case of PPP syndrome and review the relevant literature associated with this rare clinical syndrome. ...

CASE 1 A 74 year old white man presented with an abrupt onset of metacarpophalangeal (MCP) and interphalangeal (IP) joint pains associated with swelling of both hands. He had two hours of morning stiVness but no other joint complaints or history of constitutional symptoms. Past medical history was unremarkable except for diabetes mellitus type 2 treated with oral antidiabetic drugs. Examination...

Angioimmunoblastic lymphadenopathy (AILD) is a lymphoproliferative disorder with well established clinical and histological features, one of the clinical manifestations being a peripheral polyarthritis. A case of AILD with a symmetrical non-erosive peripheral polyarthritis is described, including the findings in the synovial fluid and histology of the synovium. There was a marked reduction in t...

A 34-year-old man with adult-onset Still's disease developed a striking hypercalcaemia during a rapidly destructive polyarthritis with extensive osteoporosis. The hypercalcaemia seemed to be primarily caused by inflammation-induced bone resorption. On prednisone the polyarthritis went into remission and the plasma calcium levels became normal. Other remarkable features in this case were a sublu...

Several autoimmune diseases have been reported to be associated with common variable immunodeficiency disease (CVID), including rheumatoid arthritis and Sjögren's syndrome. On the other hand, approximately 20-30% of patients with rheumatoid arthritis develop secondary Sjögren's syndrome. A 26-year-old woman had a 6-year history of chronic symmetric polyarthritis and 3-year history of sicca synd...