Thermoplastic polyamide elastomer (PAE) [also PEBA: polyether block amide] is one of the most recently developed of the thermoplastic elastomers: a multiblock polymer with polyamide hard segments, it uses longchain polyether diol or polyester diol of low Tg for its soft segments. Polyamide 6 or polyamide 12 (PA12) is the main polyamide component used, while the soft segments are mostly provided...

The purpose of this article was to review the biocompatibility, physical, and mechanical properties of the polyamide denture base materials. An electronic search of scientific papers from 1990-2014 was carried out using PubMed, Scopus and Wiley Inter Science engines using the search terms "nylon denture base" and "polyamide denture base". Searching the key words yielded a total of 82 articles. ...

Transport, mechanical and global migration data concern multilayer food packaging films with different layouts, all incorporating a layered silicate/polyamide nanocomposite as oxygen barrier layer, and a low-density polyethylene (LDPE) as moisture resistant layer in direct contact with food. The data are related to "Tuning of co-extrusion processing conditions and film layout to optimize the pe...

Recent studies show that osmotically driven membrane processes may be a viable technology for desalination, water and wastewater treatment, and power generation. However, the absence of a membrane designed for such processes is a significant obstacle hindering further advancements of this technology. This work presents the development of a high performance thin-film composite membrane for forwa...

the purpose of this article was to review the biocompatibility, physical, and mechanical properties of the polyamide denture base materials. an electronic search of scientific papers from 1990-2014 was carried out using pubmed, scopus and wiley inter science engines using the search terms “nylon denture base” and “polyamide denture base”. searching the key words yielded a total of 82 articles. ...

BACKGROUND AND OBJECTIVES Both larger molecule removal and dialyzer biocompatibility have been implicated in the high-flux hemodialysis (HD)-associated favorable outcome. In an attempt to delineate the effect of membrane permeability, we performed a randomized, crossover study to compare the inflammatory biomarkers, lipid profile, and aortic pulse wave velocity (PWV) of two dialyzers that are c...

The dentists today have to meet growing demands for prosthetic rehabilitation due to population aging and higher requirements on the quality of life. That means higher demands on the functional reliability of dental appliances, their aesthetical and biological properties. Several studies have evaluated various properties of polyamide (nylon) denture base materials. According to the results of t...

This manuscript reports the molecular basis for double-stranded DNA (dsDNA) binding of hairpin polyamides incorporating a 5-alkyl thiazole (Nt) unit. Hairpin polyamides containing an N-terminal Nt unit induce higher melting stabilisation of target dsDNA sequences relative to an archetypical hairpin polyamide incorporating an N-terminal imidazole (Im) unit. However, modification of the N-terminu...

Many cancer therapeutics target DNA and exert cytotoxicity through the induction of DNA damage and inhibition of transcription. We report that a DNA minor groove binding hairpin pyrrole-imidazole (Py-Im) polyamide interferes with RNA polymerase II (RNAP2) activity in cell culture. Polyamide treatment activates p53 signaling in LNCaP prostate cancer cells without detectable DNA damage. Genome-wi...

We recently identified a polyamide-chlorambucil conjugate, 1R-Chl, which alkylates and down-regulates transcription of the human histone H4c gene and inhibits the growth of several cancer cell lines in vitro and in a murine SW620 xenograft model, without apparent animal toxicity. In this study, we analyzed the effects of 1R-Chl in the chronic myelogenous leukemia cell line K562 and identified a...