We present a method for the electrospinning of conducting polymeric composite nanofibers using a poly(dimethyl siloxane) (PDMS)-based microfluidic device. To scale-up the process and spin multicomponent systems, we designed a unique multi-spinnerette electrospinning device using microchannels cast in PDMS. Nanofibers of poly (vinylpyrrolidone) and its composite with polypyrrole were successfull...

Glycopolymers with mannose units were readily prepared by click chemistry of an azido mannopyranoside derivative and a poly(propargyl acrylate-co-N-vinyl pyrrolidone). These glycopolymers were used as polymer surfactants, in order to obtain glycosylated polycaprolactone nanoparticles. Optimum stabilization for long time storage was achieved by using a mixture of glycopolymers and the non-ionic ...

Ultrasmall nanoparticles, with sizes in the 1-3 nm range, exhibit unique properties distinct from those of free molecules and larger-sized nanoparticles. Demonstrating that the hydrothermal method can serve as a facile method for the synthesis of platinum nanoparticles, we successfully synthesized ultrasmall Pt nanoparticles with an average size of 2.45 nm, with the aid of poly(vinyl pyrrolidon...

Poly(vinyl pyrrolidone) (PVP) was grafted onto Pluronic F127 (PEO-PPO-PEO) to produce novel amphiphilic PVP-g-F127 graft copolymers. A controlled synthesis method was used to graft PVP onto different parts of F127. Two types of graft polymers were obtained: one has PVP grafted onto the PEO part of F127 and the other has PVP grafted onto the PPO part of F127. The association behavior of the two ...

The ferrocene/Poly(vinyl pyrrolidone) (PVP) composite membranes have been successfully prepared by using electrospinning and polarization coating techniques, respectively. The composite membranes were characterized by means of SEM (scanning electron microscopy), UV-vis absorption spectra, FT-IR (Fourier transform infrared), XRD (X-ray diffraction) and a radio frequency (RF) impedance/capacitanc...

Gold-silver alloy nanocages with controllable pores on the surface have been synthesized via galvanic replacement reaction between truncated Ag nanocubes and aqueous HAuCl4. Unlike in the previous studies, the initiation of replacement reaction started in a controllable way, simultaneously from eight corners of the truncated Ag nanocubes where {111} facets were exposed. The formation of cubic n...

Intranasal route is one of the most attractive routes for distributing drugs to systemic circulation. Liposomes are used as biocompatible carriers to improve delivery properties across nasal mucosa. The objective of the present study was to formulate acyclovir liposomes and partition into poly-N-vinyl-2-pyrrolidone. Entrapment efficiency showed that multilamellar and unilamellar liposomes were ...

The work demonstrates a judicious approach to achieve hepatocyte cell-targeted highly efficient gene delivery by utilizing a supramolecular complex of galactosylated cucurbituril and dextran-spermine conjugates.