Protein synthesis is one of the most complex cellular processes, involving numerous translation components that interact in multiple sequential steps. The most complex stage in protein synthesis is the initiation process. The basal set of factors required for translation initiation has been determined, and biochemical, genetic, and structural studies are now beginning to reveal details of their...

The potential photoaffinity reagents 2,5-diazido-3-methyl6-isopropyl-l,4-benzoquinone (DAZMIB) and 2,5-diazido-3,6dimethyl-l,4-benzoquinone (DAZDMQ), which are analogs of the well-known inhibitor 2,5-dibromo-3-methyl-6-isopropyl1,4-benzoquinone (DBMIB), block photosynthetic electron transport in spinach chloroplasts. On irradiation, at relatively high concentrations, DAZMlB inhibits electron fl...

To investigate the protein-ubiquinone interaction in the bovine heart mitochondrial succinate-cytochrome c reductase region of the respiratory chain, three fluorine substituted ubiquinone derivatives, 2,3-dimethoxy-6-(9'-fluorodecyl)-1,4-benzoquinone (9FQ), 2-methoxy-5-trifluoromethyl-6-decyl-1,4-benzoquinone (TFQ), and 2-methoxy-5-trifluoromethyl-6-(9'-fluorodecyl)-1,4-benzoquinone (9FTFQ), we...

Gas-phase product detection studies of o-hydroxyphenyl radical and O2 are reported at 373, 500, and 600 K, at 4 Torr (533.3 Pa), using VUV time-resolved synchrotron photoionisation mass spectrometry. The dominant products are assigned as o-benzoquinone (C6H4O2, m/z 108) and cyclopentadienone (C5H4O, m/z 80). It is concluded that cyclopentadienone forms as a secondary product from prompt decompo...

Composites of heterospin molecular magnet [EuIII(SQ)3bipy] in a polystyrene (PS) matrix have been synthesized. This complex contains four paramagnetic centers - the Eu3+ ion and three SQ ligands (SQ—3,6-di-tert-butyl benzoquinone radical anion); bipy (bipyridyl) is diamagnetic. It has established that intensive mechanical activation [EuIII(SQ)3bipy]/PS samples leads to an reological explosion, ...

Abstract Chromophores, colored substances of rather high stability that reduce brightness, are present in all kinds cellulosic products, such as pulp, fibers, aged material, and even very low concentrations highly bleached pulps. Thus, they the prime targets industrial pulp bleaching. In this study, three key chromophores 2,5-dihydroxy-1,4-benzoquinone (DHBQ, 1 ), 5,8-dihydroxy-1,4-naphthoquino...

The antitumor agent, asterriquinone (ARQ) is a known metabolite isolated from the mycelium of Aspergillus terreus IFO 61231). YAMAMOTO et al. reported that ARQ analogues having a 2, 5-dimethoxy-p-benzoquinone moiety (ARQ dimethyl ether: ARQDMe)2,3) and the 2, 5-diamino-p-benzoquinone moiety (diamino ARQ: ARQDA)4) did not show any Cytotoxicity. As reported in our previous communication5), a new ...