BACKGROUND Many organophosphorus (OP) insecticides have either two O-methyl or two O-ethyl groups attached to the phosphorus atom. This chemical structure affects their responsiveness to oxime-induced acetylcholinesterase (AChE) reactivation after poisoning. However, several OP insecticides are atypical and do not have these structures. AIM We aimed to describe the clinical course and respons...

BACKGROUND Midazolam is commonly and safely used in poisoning management and intensive care for the control of agitated poisoned patients. Despite the introduction of newer and safer antidepressants, tricyclic antidepressants (TCAs) are still prescribed and used in many countries due to their cost-effectiveness. Severe morbidity and mortality associated with these drugs arises largely from thei...

AIMS To evaluate the association of acute organophosphate (OP) poisoning with chronic sensory and motor neurological impairment. METHODS This study concerns the third of a series of three examinations of hand strength and vibration thresholds in a two year period after acute OP poisoning among 48 Nicaraguan men. The first two examinations were performed at hospital discharge and seven weeks a...

The effect of eight weeks aerobic exercise and coriander seed extract on oxidative stress cellular energy indices heart tissue in male rats poisoned with hydrogen peroxide

Carcasses and viscera of coyotes poisoned by Compound 1080 (sodium fluoroacetate) in singledose tallow baits (SDBs) were fed to 3 coyotes, 3 domestic dogs, 4 striped skunks, and 15 black-billed magpies to determine if these species would be poisoned secondarily. Test subjects received no food other than tissues from poisoned coyotes for periods of 14 to 35 days. Total amounts of contaminated co...

OBJECTIVE To define the role of gastrointestinal (GI) decontamination of the poisoned patient. DATA SOURCES A computer-based PubMed/MEDLINE search of the literature on GI decontamination in the poisoned patient with cross referencing of sources. STUDY SELECTION AND DATA EXTRACTION Clinical, animal and in vitro studies were reviewed for clinical relevance to GI decontamination of the poisone...

BACKGROUND Poisoned patients are often treated in and discharged from pre-hospital health care settings. Studies of poisonings should therefore not only include hospitalized patients. AIMS To describe the acutely poisoned patients treated by ambulance personnel and in an outpatient clinic; compare patients transferred to a higher treatment level with those discharged without transfer; and stu...

OBJECTIVE To estimate the direct financial costs to the Sri Lanka Ministry of Health of treating patients after self-poisoning, particularly from pesticides, in a single district. METHODS Data on staff, drug, laboratory and other inputs for each patient admitted for self-poisoning were prospectively collected over a one-month period from one general hospital (2005) and five peripheral hospita...