نتایج جستجو برای: platelet count
تعداد نتایج: 247045 فیلتر نتایج به سال:
Background: Infant jaundice is one the most common causes of hospitalization in infant in the first month of birth, which is defined an abnormal increase in blood bilirubin levels. Exchange transfusion is the recommended treatment for neonatal jaundice who do not respond to phototherapy and experience dangerous complication of jaundice and signs of kernicterus. However, this treatment may lead ...
Patients with immune thrombocytopenic purpura (ITP), a disease characterized by abnormally low platelet count, are susceptible to excessive bleeding as a direct consequence. While the problem of low platelet count can be addressed fundamentally either by slowing down the rate of platelet destruction or by increasing platelet production, or both, one of the more effective means of treating ITP p...
Two hundred forty-four anemic hemodialysis patients were randomized into recombinant erythropoietin and placebo-treated groups during a 12-wk double-blind phase, followed by a 24-wk open-label period. Mean platelet count rose from the baseline value of 242 x 10(9)/L to 264 x 10(9)/L on day 5 of epoetin therapy (P < 0.001, paired t test). Mean platelet count peaked at 290 x 10(9)/L on day 40 and...
Background Pretreatment platelet count has been reported as a potential tool to predict survival outcome in several solid tumors. However, the predictive value of pretreatment platelet count remains obscure in de novo acute myeloid leukemia (AML) excluding acute promyelocytic leukemia (M3). Methods We conducted a retrospective review of 209 patients with de novo non-M3 AML in our institute ov...
Magnesium sulfate is widely used in obstetrics and is drug of choice in two important complications of pregnancy, preeclampsia and preterm labor. The antagonistic effects of magnesium sulfate on calcium ion and on platelet aggregation may lead to changes in bleeding time. This study was conducted to evaluate the effect of magnesium sulfate on bleeding time in women with threatened preterm labor...
Background: Patients undergoing cardiac surgery are at increased risk of bleeding due to multifactorial coagulopathies. In the present study, we aimed at investigating the changes in platelet count and function during and after surgery as well as determining the association of the platelet dysfunction with bleeding and transfusion requirements in these patients. Methods: A total of 40 adult pat...
Background: The significance of cTfh cells and their subsets in atherosclerosis is not well understood. We measured the frequency of cTfh subsets in patients with different degrees of stenosis using flow-cytometry. Methods: Participants included high (≥50%; n = 12) and low (<50%; n = 12) stenosis groups, as well as healthy controls (n = 6). Results: The frequency of CCR7loPD-1hiefficient-cTfh w...
platelet adherence surrounding leucocytes in a rosette formation or platelet satellitism is a rare phenomenon. this finding has been observed almost exclusively in ethylenediaminetetraacetic acid treated blood at room temperature. the mechanism underlying this phenomenon is not fully understood. in many reports of platelet satellitism platelets clump to polymorphonuclear neutrophils in healthy ...
OBJECTIVE To determine the spontaneous platelet recovery time in primary and secondary dengue infection in a tertiary care hospital. METHOD The cross-sectional observational study was conducted at Abbasi Shaheed Hospital, Karachi, from July 2010 to January 2011, and comprised 138 seropositive patients with ages 13 years and above who fulfilled the World Health Organisation criteria of probabl...
Several genetic variants associated with platelet count and mean platelet volume (MPV) were recently reported in people of European ancestry. In this meta-analysis of 7 genome-wide association studies (GWAS) enrolling African Americans, our aim was to identify novel genetic variants associated with platelet count and MPV. For all cohorts, GWAS analysis was performed using additive models after ...
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