extramedullary plasmacytoma is a rare neoplasm characterized by monoclonal proliferation of plasma cells. most lesions occur in the head and neck, primarily in the upper aerodigestive tract. the nasal cavity and nasal septum are the most common sites of occurrence. in this report, three patients admitted in our clinic with history of nasal obstruction and/or epistaxis. patients were diagnosed w...

Solitary plasmacytoma of the skull is very rare and only a few cases have been reported in the English literature. Skull solitary plasmacytoma tends to disseminate or progress to multiple myeloma (MM) during follow-up. If the skull lesion is isolated, couple with tenderness and marked swelling in the area, plasmacytoma should be considered, especially for the lesion showing isointense with the ...

Breast plasmacytoma is an extremely rare tumor. It can occur as a primary isolated tumor or as an extramedullary manifestation in multiple myeloma. This report describes the unusual case of a primary extramedullary plasmacytoma that progressed to multiple myeloma within 15 months in a 35-year-old woman. The patient had been initially diagnosed with a primary extramedullary plasmacytoma of the e...

Primary extramedullary plasmacytoma is an indolent neoplasm that infrequently converts to multiple myeloma. Since cytogenetic data on extramedullary plasmacytoma are lacking, we studied 38 cases of this type of neoplasm by fluorescence in situ hybridization. Fourteen cases (37%) contained IGH breaks, including six with a t(4;14) translocation. No translocations t(11;14), t(14;16), t(8;14), nor ...

abstract a solitary plasmacytoma of bone occurs in approximately 2-5% of patients with myeloma. the lesion mostly found in the axial skeleton and have infrequently been reported to arise in the hand, and usually occur in the distal phalanges. we report the interesting case of a 75-year-old man who developed a solitary lytic lesion of the thumb proximal phalanx. this lesion was explored through ...

Plasmacytoma is a neoplasm of bone marrow. It originates from plasma cells, the last maturation stage of B lymphocytes [1–3]. Plasmacytoma may appear as three different clinical disease: multiple myeloma (sistemic disease), solitary plasmacytoma (localized bone disease) and extramedullary plasmacytoma [4–6]. Bone destruction, bone pain and pathological fractures are the most common signs of the...

This report describes a case of gastric plasmacytoma which was diagnosed following an episode of haematemesis and melaena. The patient had a previous orbital plasmacytoma and subsequently developed aggressive disseminated disease with extensive skin and subcutaneous deposits but without marked marrow involvement until the terminal phase. Following the episode of haematemesis and melaena, endosc...

Plasmacytoma is a malignant plasma cell tumor growing within soft tissue or the axial skeleton. Here, we present the case of a patient with plasmacytoma of the axis vertebra who underwent decompressive surgery with reconstruction via a posterior approach. The patient was referred because of quadriparesis with severe neck pain. Magnetic resonance imaging revealed a relatively demarcated, highly ...

BACKGROUND: Solitary extramedullary plasmacytoma of the parotid gland is a rare condition. Intracytoplasmic Crystalline inclusions in the tumor are even rarer and have been reported only once in the parotid gland. CASE PRESENTATION: We report here, a case of plasmacytoma of the parotid gland with intracellular crystalline inclusions in a 73-year-old woman CONCLUSION: Solitary extramedullary pla...

Plasmacytoma is a plasma cell neoplasm that locally infiltrates a bone or spreads to extramedullary areas. A new World Health Organization criterion defines solitary plasmacytoma of bone as a localized bone tumor consisting of plasma cells identical to those seen in plasma cell myeloma, which is manifested as a solitary osteolytic lesion in a radiological evaluation. Primary tumors of the stern...