conclusions the results of the present investigation suggest that sac could be used as a food supplement in the treatment of diabetes characterized by provoked antioxidant status, altered blood glucose, and hormones level. results the levels of glucose, cyp2e1 activity, thiobarbituric acid reactive substances (tbars), hydroperoxide, and ceruloplasmin were increased significantly; whereas, the l...

The liver and beta cells function in a negative feedback loop, which appears to have a predominant role in regulating both the basal plasma glucose and insulin concentrations. The degree of basal hyperglycemia in diabetes probably provides a bioassay of both the effect of a reduction in insulin secretory capacity and the degree of insulin resistance. A mathematic model of the interaction of ins...

OBJECTIVE The dysregulation of adipokines is closely associated with the pathogenesis of insulin resistance and type 2 diabetes. Retinol-binding protein-4 (RBP4), a new adipokine, was recently reported to provide a link between obesity and insulin resistance. Here, we examined the relation between plasma RBP4 concentrations and various metabolic parameters in humans. RESEARCH DESIGN AND METHO...

BACKGROUND The role of antioxidants in the pathogenesis of type 2 diabetes is uncertain. OBJECTIVE We evaluated cross-sectional relations of dietary intakes and plasma concentrations of antioxidants with glucose metabolism in a high-risk population. DESIGN The subjects were 81 male and 101 female first- and second-degree, nondiabetic relatives of patients with type 2 diabetes. Antioxidant i...

Peripheral venous (plasma) insulin and C-peptide concentrations were measured in eight normal subjects given oral or intravenous glucose sufficient to produce similar plasma glucose concentrations. The expected increased insulin response to oral as compared with intravenous glucose was not matched by a comparable increase in C-peptide concentration. The ratio of insulin to C-peptide concentrati...

conclusions in conclusion, taking gse for eight weeks had beneficial effects on the plasma gsh, mda levels, and markers of insulin metabolism of female volleyball players. results supplementation with gse resulted in a significant rise in the plasma glutathione (gsh) level (+265.5 ± 344.2 vs. +2.2 ± 378.2 µmol/l, p = 0.02), as well as a significant decrease in the malondialdehyde (mda) level (-...

the purpose of the present study was to investigate the effect of endurance (et), resistance (rt) and concurrent training (ct) on plasma levels of visfatin, insulin, glucose and insulin resistance of non-athlete men with obesity. it was a semi-experimental study. thirty six men [age: 21.48 (0.25), and bf%: 27.39 (0.52)], voluntarily participated in this study after public announcement in univer...

Plasma glucose and insulin responses to a graded i.v. infusion of glucose were compared in two groups of glucose-tolerant women divided on the basis of their insulin sensitivity. Resistance to insulin-mediated glucose disposal was measured using the insulin suppression test, and the women studied were chosen to represent the highest and lowest quartiles of insulin resistance seen in the normal ...

background: s-methyl cysteine (smc) is a hydrophilic cysteine-containing compound naturally found in garlic and onion. the purpose of the present study was to investigate the protective effect of smc on oxidative stress, inflammation and insulin resistance in an experiment of metabolic syndrome. methods: male wistar rats were divided into five groups (6 rats in each group), namely; control, con...