A placebo-controlled, randomized, double-blind, parallel-group, comparative, multicenter study was conducted to investigate the efficacy and safety of benzoyl peroxide (BPO) gel, administrated once daily for 12 weeks to Japanese patients with acne vulgaris. Efficacy was evaluated by counting all inflammatory and non-inflammatory lesions. Safety was evaluated based on adverse events, local skin ...

A heme-iron concentrate product derived from swine hemoglobin was used to enrich the chocolate-flavored filling of biscuits and the bioavailability of this source of heme-iron was assessed in adolescent girls. The placebo control (PC) group consisted of 35 teenagers with the highest baseline hemoglobin concentrations. The supplemented groups were randomized to receive biscuits fortified with ir...

Placebo is the second-best remedy in Homoeopathy. In day-to-day practice certain situation arise which lead us to prescribe placebo. Beginning from case taking when patient some medicines, end of treatment homoeopathic aggravation occurs, all that time physician requires middle process placebo needed during aggravation, improvement case. Certain disease conditions like Artificial Chronic Diseas...

Abstract BACKGROUND Newly diagnosed glioblastoma (nGBM) has a dismal prognosis with survival of 15-18 months. Tumor associated “survivin” protein is expressed in >95% nGBM and targetable the use SurVaxM, shown to be effective at generating cytotoxic T lymphocytes. METHODS patients are being enrolled this randomized placebo-controlled trial phase II study. Eligibility Criteria includes ag...

The purpose of the present study was to examine placebo and nocebo effects under hypnotic analgesia in lowly hypnotizable (LH) highly (HH) subjects. A nocebo, obtained a two-step intervention (verbal expectation conditioning), were studied 12 LH HH subjects hypnosis. Visual analog scales (VASs) pain intensity recorded response short, painful electrical stimuli. VAS scores placebo-produced diffe...

This article reviews the role of placebo interventions and placebo effects in clinical practice. We first describe the relevance of different perspectives among scientists, physicians and patients on what is considered a placebo intervention in clinical practice. We then summarize how placebo effects have been investigated in randomized controlled trials under the questionable premise that such...

background oral administration of pro- and prebiotics has recently been considered as an effective way for nonalcoholic fatty liver disease (nafld) recovery. objectives the current study aimed at evaluating the effect of supplementation with probiotics and/or prebiotics on liver function tests in patients with nafld. methods in this double blind, placebo-control clinical trial, 75 subjects with...