Small self-cleaving ribozymes have been discovered in all evolutionary domains of life. They can catalyze site-specific RNA cleavage, and as a result, they have relevance in gene regulation. Comparative genomic analysis has led to the discovery of a new class of small self-cleaving ribozymes named Pistol. We report the crystal structure of Pistol at 2.97-Å resolution. Our results suggest that t...

PURPOSE To evaluate the outcome of 20 claw hands corrected with the Zancolli lasso procedure. METHODS 20 patients aged 7 to 48 (mean, 28) years with claw hand deformity for a mean of 33.3 months secondary to leprosy (n=17), traumatic ulnar nerve injury (n=2), or tardy ulnar nerve palsy (n=1) underwent the Zancolli lasso procedure, in which the flexor digitorum superficialis (FDS) of the middl...

We present new infrared images, obtained with the Hubble Space Telescope (HST) Near-infrared Camera and Multi-object Spectrometer (NICMOS), and Br-α (4.05 μm) spectroscopy, obtained using CGS4 on UKIRT, of the Pistol Star and its associated nebula. We find strong evidence to support the hypothesis that the Pistol Nebula was ejected from the Pistol Star. The Pa-α (1.87 μm) NICMOS image shows tha...

In this study the alpha band waves of low to moderately skilled pistol shooters are evaluated to examine the performance of the individuals under a competitive environment. The factors that cater to success in the autonomous stage of learning are different for the athlete. There has been investigation of the brain patterns of experts, while performing a task is efficient and in accord with Fitt...

The objective of the case report is to discuss a patient with crush injury over right forearm. A 37 years old male came complain pain, swelling, restricted range affected side, muscle weakness forearm, wrist and hand, reduced grip strength on difficulties in ADL’S right-hand following Treatment involved physical therapy Electro modalities for elimination pain returning patient’s full motion han...

The ulnar nerve is most commonly involved in leprosy and is affected at or just above the elbow. The outcome of this damage is paralysis of the intrinsic muscles of the hand with the exception of the thenar group, together with paresis of ring and little finger flexor digitorum profundus (FDP). Although the obvious deformity is clawing of the fingers, other deformities are produced: 1. Hollowin...

BACKGROUND During the last years, terms like acetabular retroversion, excessive overcoverage, and abnormal head-neck-junction with the so called "pistol-grip-deformity" has been added to the classical description of hip dysplasia. These anatomical changes could lead to a femoroacetabular impingement (FAI). Both kinds of FAI has been indentified as a main reason for hip pain and progressive dege...

OBJECTIVE To find the best clinical parameters for defining and classifying the degree of plantar plate injuries. METHOD Sixty-eight patients (100 metatarsophalangeal joints) were classified in accordance with the Arthroscopic Anatomical Classification for plantar plate injuries and were divided into five groups (0 to IV). Their medical files were reviewed and the incidence of each parameter ...

he principles regarding impingement in the natural osseous (anatomic) hip put forth by Ganz et al. are similar in concept to what can occur in the prosthetic hip. To understand impingement, it is helpful to recognize the common mechanisms that cause mechanical abutment in both anatomic and prosthetic hips. In the anatomic hip joint, impingement is a mechanical abutment conflict between the bone...