نتایج جستجو برای: piperacillin

تعداد نتایج: 2563  

Journal: :Infection control and hospital epidemiology 2004
Usha Stiefel David L Paterson Nicole J Pultz Steven M Gordon David C Aron Curtis J Donskey

BACKGROUND The substitution of piperacillin/tazobactam, ampicillin/sulbactam, or both for third-generation cephalosporins has been associated with reduced vancomycin-resistant enterococci (VRE). However, piperacillin/tazobactam came into widespread use during a period in which the prevalence of VRE increased. We hypothesized that the increasing use of piperacillin/tazobactam and other agents wi...

Journal: :Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2010
Fiona L M Chew T K Soong Hoy Choong Shin A Samsudin Subrayan Visvaraja

PURPOSE To report the treatment of therapy-resistant Pseudomonas aeruginosa keratitis with topical piperacillin/tazobactam. METHODS Retrospective report of 3 cases. RESULTS Three patients with P. aeruginosa keratitis were unresponsive to various antimicrobials. Resolution of all 3 cases of keratitis occurred upon commencement of topical piperacillin/tazobactam. CONCLUSION Therapy-resistan...

Journal: :Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 2010
Shakir Hussain Shakir Syed Khalid Baloch

Electrolytes imbalance has been reported with the use of several antimicrobials. We report a case of severe hypokalemia secondary to piperacillin/tazobactam in a patient with normal renal function and normal serum potassium level who had presented with a fractured neck of femur. The electrolytes abnormality was corrected once piperacillin/tazobactam was stopped. To our knowledge, this is the fi...

Journal: :Antimicrobial agents and chemotherapy 1981
S J Landis R Ramphal B J Mansheim K H Rand J W Shands

The comparative efficacy of 2 g of piperacillin and 4.8 X 10(6) U of penicillin G in the treatment of uncomplicated gonococcal urethritis was assessed in a randomized prospective study. Sixty-five evaluable patients received piperacillin, and 55 received penicillin G. All patients received either therapy were cured of gonorrhea. We conclude that piperacillin is as efficacious as aqueous procain...

2015
Andrew A Udy Jeffrey Lipman Paul Jarrett Kerenaftali Klein Steven C Wallis Kashyap Patel Carl MJ Kirkpatrick Peter S Kruger David L Paterson Michael S Roberts Jason A Roberts

INTRODUCTION The aim of this study was to explore the impact of augmented creatinine clearance and differing minimum inhibitory concentrations (MIC) on piperacillin pharmacokinetic/pharmacodynamic (PK/PD) target attainment (time above MIC (fT>MIC)) in critically ill patients with sepsis receiving intermittent dosing. METHODS To be eligible for enrolment, critically ill patients with sepsis ha...

2016
Tat Ming Ng Wendy X Khong Patrick N A Harris Partha P De Angela Chow Paul A Tambyah David C Lye

Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae are a common cause of bacteraemia in endemic countries and may be associated with high mortality; carbapenems are considered the drug of choice. Limited data suggest piperacillin-tazobactam could be equally effective. We aimed to compare 30-day mortality of patients treated empirically with piperacillin-tazobactam versus a car...

Journal: :Hospital pharmacy 2015
Jennifer Wade Mandelin Cooper Robert Ragan

PURPOSE To evaluate the physical compatibility of vancomycin with piperacillin-tazobactam during simulated Y-site administration. METHODS Vancomycin and piperacillin-tazobactam were tested using 2 different diluents: 0.9% sodium chloride and 5% dextrose for injection. Vancomycin concentrations of 2, 5, and 10 mg/mL were tested using 0.9% sodium chloride and 4 and 8 mg/mL in 5% dextrose. Piper...

Sub Minimal Inhibitory concentrations (sub-MIC) of antibiotics, although not able to kill bacteria, can be effect on their physico- chemical characteristics and functions. This study aimed to investigate the effect of sub-MIC of imipenem and piperacillin on the transcriptional expression of virulence related genes algD and lasB in Pseudomonas auroginosa. Five clinical isolates of P. aeruginosa ...

Journal: :Antimicrobial agents and chemotherapy 1998
L M Ednie M R Jacobs P C Appelbaum

Activities of clinafloxacin, ciprofloxacin, levofloxacin, sparfloxacin, trovafloxacin, piperacillin, piperacillin-tazobactam, trimethoprim-sulfamethoxazole, ceftazidime, and imipenem against 354 ciprofloxacin-susceptible and -intermediate-resistant organisms were tested by agar dilution. Clinafloxacin yielded the lowest quinolone MICs (< or = 0.5 microg/ml against ciprofloxacin-susceptible orga...

Journal: :Antimicrobial agents and chemotherapy 2008
So-Young Lee Jin Kyung Yu Sang Yoon Lee Sang Hyun Shin Hae-Il Park Eun-Jee Oh Yeon-Joon Park

The VITEK 2 (bioMérieux Inc., Hazelwood, MO) automated system employs an advanced expert system (AES) analyzing antimicrobial susceptibility test results according to the bacterial species (2). According to the AES, the piperacillin susceptibilities of all Klebsiella spp. are converted to resistance even though the automated MICs determined for their isolates are low. In contrast, other automat...

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