Background and objectives: The cholinergic deficit correlates with the severity of Alzheimer’s disease. The cholinergic function can be improved by AChE inhibitors blocking this key enzyme in the breakdown of acetylcholine. Based on traditional medicine, during two last decades the use of herbal medicinal substances in dementia therapy has been studied. The fruit extract of <em...

The emergence of drug-resistant Tuberculosis has become a global health problem. Herbal drugs promise other potential options for treatment. This study aimed to investigate the anti-mycobacterial activity three plants: Piper longum, Cressa cretica and Calotropis gigantea. methanolic extract these plants was tested against Mycobacterium tuberculosis H37Rv using BACTEC MGIT-960 Automated system, ...

Natural infection of Cucumber mosaic virus (CMV) in Indian long pepper (Piper longum L.) and betel vine (Piper betle L.) was detected by reverse transcription polymerase chain reaction (RT-PCR). The coat protein gene sequences of CMV infecting these hosts were amplified. The resulting amplicons were cloned and sequenced. In both the cases coat protein gene consisted of 657 nucleotides, potentia...

A simple, rapid and precise spectrophotometric method has been developed for the estimation of piperine in Ayurvedic formulation Chitrakadi Vati. Three marketed preparations of Chitrakadi Vati containing black pepper (Piper nigrum) and pippali (Piper longum) from different manufacturer (CV-1, CV-2 and CV-3) were taken in this study to estimate the % w/w of piperine. The % w/w content of piperin...

antimicrobial activity of plant extracts in traditional medicine on bacteria and fungi has been identified. medicinal plants have been used since ancient times as a food coloring and flavoring agents. also, plant extracts have been used for the prevention of diseases caused by food borne pathogens. with the use of active packaging that can interact with the environment and product, increased sh...

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This study investigated the effects of some plant extracts on the bacterial communication system, expressed as quorum sensing (QS) activity. Quorum sensing has a directly proportional effect on the amount of certain compounds, such as pigments, produced by the bacteria. Alcohol extracts of 23 ornamental and medicinal plants were tested for anti-QS activity by the Chromobacterium violaceum assay...

A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effe...

The present study was undertaken to assess the biochemical changes in goats treated with anthelmintic indigenous herbs. The analysis of data was done in 18 goats, irrespective of age, sex and breed. The experimental goats were randomly divided in six groups. The effect of crude powder and cold aqueous extract of Nigella sativa, Swertia chirata and Piper longum was studied on various biochemical...