BACKGROUND Outcome measures for atopic dermatitis (AD) patients with pigmented skin have neither been developed nor validated. OBJECTIVE To compare the reliability and validity of four common AD outcome measures in patients with various levels of skin darkness. METHOD The inter- and intra-rater reliability and construct validity of the EASI (Eczema Area and Severity Index), objective-SCORin...

Dermoscopy is an in vivo method for the early diagnosis of malignant melanoma and the differential diagnosis of pigmented lesions of the skin. It has been shown to increase diagnostic accuracy over clinical visual inspection in the hands of experienced physicians. This article is a review of the principles of dermoscopy as well as recent technological developments.

Whether the diagnosis of any particular nevus is problematic or not depends upon a variety of factors, including the experience and enthusiasm of the pathologist, the nature of the specimen (shave vs. punch vs. excisional), the quality of the sections (and their staining), the hour of the day or day of the week in addition to the problems relating to the ever-increasing range of histological va...

OBJECTIVES To determine whether an aid to the diagnosis of pigmented skin lesions reduces the ratio of benign lesions to melanomas excised in general practice. DESIGN Controlled trial randomised by practice. SETTING General practices in Perth, Western Australia. PARTICIPANTS 468 general practitioners in 223 practices. INTERVENTIONS Intervention practices were given an algorithm and inst...

Patients with HIV have higher risk of developing squamous cell carcinoma of the skin given the increased risk of HPV infection, which alters cell proliferation and apoptosis [1]. Pigmented Bowen's disease is an uncommon form of squamous cell carcinoma in-situ characterized by pigmented lesions that can clinically mimic superficial spreading melanoma, pigmented basal cell carcinoma, melanocytic ...

Background: Evaluation and treatment of pigmented skin lesions is one of the most common reasons for dermatologic consultation. The vast majority of these are completely benign in nature without any risk of malignant transformation. However, these pigmented lesions occasionally exhibit more concerning features of dysplasia, ranked from mild to severe in degree. The most concerning pigmented les...

Objectives To determine whether an aid to the diagnosis of pigmented skin lesions reduces the ratio of benign lesions to melanomas excised in general practice. Design Controlled trial randomised by practice. Setting General practices in Perth, Western Australia. Participants 468 general practitioners in 223 practices. Interventions Intervention practices were given an algorithm and instant came...

Bowens' disease (BD) is a precancerous condition of skin and/or mucosa with a predilection towards sun-exposed areas. Extensive literature research failed to reveal any case of multiple pigmented BD in type V Fitzpatrick skin. Multiple BD is a therapeutic challenge with a tendency to recur. Here we present an otherwise healthy Indian male having multiple pigmented lesions of BD on sun-protected...