Background:-Hypopigmentary disorders constitute a large and heterogenous group of diseases that are clinically characterised by hypopigmented macules .Dermoscopy is non invasive imaging technique allows for appreciation subtle, distinctive features visible to the naked eye aid in differential diagnosis hypopigmentary disorders. Aims &Objective:- To investigate utility dermoscopy In common d...

OBJECTIVE To determine the prevalence and pattern of skin disorders among female schoolchildren in primary and intermediate schools in Al-Khobar city, Eastern Saudi Arabia. METHODS This is a cross-sectional study conducted in Al-Khobar city, Kingdom of Saudi Arabia during the period from January-March 2003. It involved 2239 female schoolchildren randomly selected from 30 regular public and pr...

Balakrishnan Nirmal Department of Dermatology, Christian Medical College, Vellore, Tamil Nadu, India Dermatoscopy has become increasingly significant in assisting the diagnosis of common dermatological disorders.[1] However, the main deterrent to the utility of dermatoscopy in dark skin is the presence of higher melanin content in the basal layer preventing deeper pigmentation and vessels from ...

lentiginosis prompted eval¬ uation for a unifying diagnosis. Disorders of pigmentation have been reported in association with various cardiac abnormalities, but classification remains controversial. Features of both cardiomyopathic lentiginosis2 and LEOPARD syndrome,3-5 a mnemonic code for Zentiginosis, ECG changes, ocular hypertelorism, pulmonic steno¬ sis, abnormal genitalia, growth retardati...

Background: Melanin pigmentation of the gingiva occurs in allethnicities. Excessive pigmentation is an esthetic concern thathas increased awareness about depigmentation procedures. Thepurpose of the present study was to correlate the skin color andgender with the intensity and distribution of gingival melaninpigmentation in a group of South Indians for treatment strategies.Method: Two hundred m...

Cellular homeostasis is an outcome of complex interacting processes with nonlinear feedbacks that can span distinct spatial and temporal dimensions. Skin tanning is one such dynamic response that maintains genome integrity of epidermal cells. Although pathways underlying hyperpigmentation cascade are recognized, negative feedback regulatory loops that can dampen the activated melanogenesis proc...

Merle is a pattern of coloring observed in the coat of the domestic dog and is characterized by patches of diluted pigment. This trait is inherited in an autosomal, incompletely dominant fashion. Dogs heterozygous or homozygous for the merle locus exhibit a wide range of auditory and ophthalmologic abnormalities, which are similar to those observed for the human auditory-pigmentation disorder W...

This article investigates the extent to which the emerging trend of do-it-yourself anti-ageing skin-whitening products represents a re-articulation of Western colonial concerns with environmental pollution and racial degeneracy into concern with gendered vulnerability. This emerging market is a multibillion dollar industry anchored in the USA, but expanding globally. Do-it-yourself anti-ageing ...

Inflammation-associated pigmentation changes are extremely common, but the etiology underlying this clinical observation remains elusive. Particularly, it is unclear how the myriad of cytokines known to be involved in inflammatory skin processes affect epidermal melanocytes. We sought to determine how IL-17 and tumor necrosis factor (TNF) influence normal human melanocytes, as these two cytokin...