FMD virus is an aphtovirus within the picornaviridae family. The most important characteristics in the epidemiology of the disease include the rapid growth of the virus, its stability under a variety of conditions and the occurrence of serotypes (Donaldson, 1991). There are seven serotypes and several subtypes within each. The infections caused by different serotypes are clinically indistinguis...

An easily learned convention for systematizing the nomenclature of picornavirus proteins is described. The convention is based upon an idealized map, called the L434 diagram, of the picornavirus polyprotein.

UNLABELLED Encephalomyocarditis virus (EMCV) is a member of the Cardiovirus genus within the large Picornaviridae family, which includes a number of important human and animal pathogens. The RNA-dependent RNA polymerase (RdRp) 3Dpol is a key enzyme for viral genome replication. In this study, we report the X-ray structures of two different crystal forms of the EMCV RdRp determined at 2.8- and 2...

The molecular classification of the porcine enterovirus (PEV) groups II and III was investigated. The sequence of the almost complete PEV-8 (group II) genome reveals that this virus has unique L and 2A gene regions. A reclassification of this group into a new picornavirus genus is suggested. PEV group III viruses are typical enteroviruses. They differ from other enteroviruses by a prolonged ste...

Hepatitis in ducks can be caused by at least three different viruses. The more common and 4 internationally widespread is duck hepatitis virus (DHV) type I, a member of the Picornaviridae in 5 the proposed new genus Avihepatovirus [now designated as an unclassified picornavirus], which causes 6 a highly lethal, acute, contagious infection in ducklings under 6 weeks of age and, frequently, under...

Hand, foot, and mouth disease (HFMD) affects infant and young children. A viral metagenomic approach was used to identify the eukaryotic viruses in fecal samples from 29 Thai children with clinical diagnosis of HFMD collected during the 2012 outbreak. These children had previously tested negative by PCR for enterovirus 71 and coxsackievirus A16 and A6. Deep sequencing revealed nine virus famili...

Human parechoviruses (HPeVs) belonging to the family Picornaviridae are widely spread pathogens among young children. We report the complete genome sequence of a novel HPeV isolated from the stool sample of a hospitalized child with diarrhea in China. The genome consists of 7,305 nucleotides, excluding the 3' poly(A) tail, and has an open reading frame that maps between nucleotide positions 675...

Within the last decade, a large number of viruses genetically related to human hepatitis have been identified in different animal species, including monkeys. Numerous A virus (HAV, Picornaviridae: Hepatovirus: Hepatovirus A) were detected various mammalian species 20152018, predominantly bats and rodents, but also shrews, seals marsupials. Zoonotic E (HEV, Hepeviridae: Orthohepevirus: Orthohepe...