Context: Five species of the genus Ajuga (Lamiaceae) having common name "bugle" are found in Iran. In Persian medicine (PM), (Kamaphytus) is used for treating jaundice, joint pain, gout, amenorrhea, sciatica, and wound healing. This study aimed to review ethnobotanical, phytochemical, biological activities that grow Iran determine their therapeutic potentials suggest further studies on healing ...

The ecdysone-inducible gene switch is a useful tool for modulating gene expression in mammalian cells and transgenic animals. We have identified inducers derived from plants as well as certain classes of insecticides that increase the versatility of this gene regulation system. Phytoecdysteroids share the favorable kinetics of steroids, but are inert in mammals. The gene regulation properties o...

The possibility of an express assessment of quality medicinal raw materials Rhaponticum carthamoides (Willd.) Iljin is investigated, at various stages of harvesting and storage by method Bromic Antioxidant Capacity Estimation (BACE), after extraction of sample in an aqueous solution. Revealed that phytoecdysteroids R. carthamoides extracted in aqueous solution at level of ethanol, have the temp...

Three new phytoecdysteroid compounds, named niuxixinsterone A (1), B (2) and C (3) with acetal functions in the side-chain were isolated from Achyranthes bidentata Bl. The structures were established as (20R,22R,24S)-20-O,22-O-(5'-hydroxymethyl)-furfurylidene-2β,3β,14α,25-tetrahydroxy-5β-ergost-7-en-6-one (1), (20R,22R)-20-O,22-O-(5'-hydroxymethyl)-furfurylidene-2β,3β,25-trihydroxy-14β-methyl-1...

Skeletal muscle is the most abundant tissue in the adult human body, comprising more than 40% of total body mass in normal, healthy individuals [1], and is required for movement and locomotion. Muscle mass (volume) is an important determinant of muscle function, such that physiological cross-sectional area is correlated to peak isometric force [2,3]. The maintenance of skeletal muscle mass exis...