BACKGROUND The purpose of this study was to evaluate changes in subfoveal choroidal thickness after photodynamic therapy in patients with acute idiopathic central serous chorioretinopathy (ICSCR). METHODS This was a retrospective observational study conducted in 63 participants. The primary outcome measure was subfoveal choroidal thickness at baseline and 3 days, one week, 4 weeks, and 12 wee...

INTRODUCTION The aim of this study is the evaluation of the effect of Antimicrobial Photodynamic Therapy with Radachlorin on Staphylococcus aureus and Escherichia coli. New windows are open in the antimicrobial field so-call Photodynamic therapy that incorporates a nonpoisonous photosensitizer (PS) with innocuous special wavelength photons to excite the PS. METHODS Two strains of bacteria use...

introduction: the aim of the present study was to evaluate the effect of photodynamic therapy in the treatment of experimental corneal neovascularization (nv) with benzoporphyrin derivative (bpd). methods: one group was considered as control (n=6 eyes) then, corneal nv was induced in 30 new zealand male rabbits (n=60 eyes) by placing 7.0 silk sutures at midstromal depth approximately1mm from th...

conservation of deciduous teeth with pulp alterations caused by caries or trauma is a major therapeutic challenge in pediatric dentistry. it is essential that the sanitizers used in root canal procedures perform well in eliminating bacteria. antimicrobial photodynamic therapy (pdt) is an emerging and promising adjuvant therapy for endodontic treatment in an attempt to eliminate microorganisms p...

In this paper we evaluated the efficacy of photodynamic treatment of infected wounds on pig animal model by diffuse reflectance spectrometry. The study was conducted on fifteen wounds contaminated with Staphylococcus aureus bacteria that were incubated for 30 min with methylene blue solution (c = 3.3 x 10 M) and exposed to laser radiations (λ = 670 nm, P = 15 mW) for 15 min. The efficiency of p...

The system of partial differential equations describing tumor-immune dynamics with angiogenesis taken into account is presented. For spatially homogeneous case, the steady state analysis of the model is carried out. The effects of single photodynamic impact are numerically simulated. In the case of strong immune response we found that the photodynamic therapy (PDT) gives rise to the substantial...

BACKGROUND Dermatophytes are filamentous keratinophilic fungi. Trichophyton rubrum is a prevalent infectious agent in tineas and other skin diseases. Drug therapy is considered to be limited in the treatment of such infections, mainly due to low accessibility of the drug to the tissue attacked and development of antifungal resistance in these microorganisms. In this context, Photodynamic Therap...

The biomechanical performance of a locking compression plate system was compared to an intramedullary photodynamic bone stabilization system in a femur and humerus osteotomy model. The photodynamic bone stabilization system utilizes an angioplasty-like balloon that is introduced into the intramedullary canal of a fractured bone, filled with monomer that is then polymerized and hardened by visib...

Photodynamic therapy has a role in the management of early and late thoracic malignancies. It can be used to facilitate minimally-invasive treatment of early endobronchial tumours and also to palliate obstructive and bleeding effects of advanced endobronchial tumours. Photodynamic therapy has been used as a means of downsizing tumours to allow for resection, as well as reducing the extent of re...

Photodynamic therapy (PDT) kills cancer cells by converting tumour oxygen into reactive singlet oxygen ((1)O2) using a photosensitizer. However, pre-existing hypoxia in tumours and oxygen consumption during PDT can result in an inadequate oxygen supply, which in turn hampers photodynamic efficacy. Here to overcome this problem, we create oxygen self-enriching photodynamic therapy (Oxy-PDT) by l...