Synthesis of a series of new 1, 3, 2dioxaphosphinane derivatives (3a-j) was accomplished. The key step in the synthesis of 3a-j involves the cyclization reaction of tris (hydroxy methyl) nitromethane (1) with P(X)Cl3 (X=S,O) in presence of TEA in THF at 40-45 °C to afford the phosphoryl mono chloride intermediate (2). The intermediate (2) when treated with different substituted aromatic amines ...

siilver tetrafluoroborate complex of 5.11.17.23-tetra-tert-butyl-25-26,27,28-tetrakis (diphenylphosphinoylmethoxy)calyx[4]arene (l) has been synthesized by reaction of silver tetrafluoroborate and l in dichloromethane at room temperature. the complex formed has a 1:1 metall/ligand ratio. 1h and 31p nmr data support an encapsulated structure of the complex in which silver ion is located inside t...

In an endeavor to find a novel series of antihyperglycemic agents, new benzimidazole and pyrimidine derivatives were successfully synthesized efficiently in high yield with high purity, starting from amino acids in the presence of phosphorus oxychloride (POCl3). The synthesized compounds were identified by (1)H-NMR, (13)C-NMR, FT-IR spectroscopic techniques and elemental analysis. All products ...

6-[(4-Methoxy/4,9-dimethoxy)-7-methylfurochromen-5-ylideneamino]-2-thioxo-2,3-dihydropyrimidin-4-ones 1a,b were prepared by reaction of 6-amino-2-thiouracil with visnagen or khellin, respectively. Reaction of 1a,b with methyl iodide afforded furochromenylideneaminomethylsulfanylpyrimidin-4-ones 2a,b. Compounds 2a,b were reacted with secondary aliphatic amines to give the corresponding furochrom...

To detect POCl3 molecule, adsorption phenomena of this molecule on the pure, Al- and Si-doped BN sheet surfaces were investigated via density functional theory (DFT) approach. The most stable adsorption complexes, including POCl3/BN (O-B), POCl3/Al-BN (O-Al), and POCl3/Si-BN (O-Si), were predicted with the adsorption energies of about -8.64, -37.01 and, -62.01 kcal mol-1, respectively. Upon the...

Pyruvate, phosphate dikinase from Bacteroides symbiosus catalyzes the conversion of pyruvate, ATP, and Pi to Penolpyruvate, AMP, and PP,. Initial velocity studies by both the forward and reverse reactions in which the three substrates were varied in a constant ratio were found to be in accord with a Tri Uni Uni Ping Pong mechanism. The reaction involves three partial reactions which were invest...