The research involved a rapid, automated and highly accurate developed CFIA/MZ technique for estimation of phenylephrine hydrochloride (PHE) in pure, dosage forms biological sample. This method is based on oxidative coupling reaction 2,4-dinitrophenylhydrazine (DNPH) with PHE existence sodium periodate as oxidizing agent alkaline medium to form red colored product at ʎmax )520 nm (. A flow rate...

PURPOSE The aim of this study was to investigate the time-course of changes in choroidal thickness (ChT) following complete mydriasis induced by compound tropicamide. METHODS ChT was measured by OCT with the enhanced-depth imaging technique (Spectralis HRA+OCT, Heidelberg Engineering, Germany) at nine locations of the fundus: subfoveal ChT (SFChT) and ChT at 1 mm and 3 mm from the fovea in fo...

A liquid chromatographic method was applied for the analysis of two sustained-release mixtures containing dextromethorphane hydrobromide, carbinoxamine maleate with either phenylephrine hydrochloride in pharmaceutical capsules (Mix 1) or phenyl-propanolamine, methylparaben, and propylparaben, which bonds as a drug base to ion exchange resin in pharmaceutical syrup (Mix 2). The method was used f...

Heat, acid, base, UV radiation and oxidation stress methods were applied to study the stability of cough-cold products containing acetaminophen, phenylephrine or phenylpropanolamine hydrochloride and chlorpheniramine maleate. Liquid chromatography coupled with mass spectrometry was used to analyze the degraded samples and obtain molecular weights information. Different volatile buffers (ammoniu...

Acetaminophen, phenylephrine and chlorpheniramine are frequently associated in pharmaceutical formulations against the common cold. Their quantification presents several problems. A HPLC method for the simultaneous determination of these compounds in pharmaceutical formulations such as capsules and sachets, including the separation of impurities and excipients has been developed and validated. ...

A short-cut method is given for calculating grouped maximum likelihood (ML) estimates when the data are relatively coarsely grouped in some directions, but more finely grouped in others. The algebraic details are then worked out for a dose-response problem that generates data of this kind. The situation envisaged is a variation on the usual quantal response problem in that dosage levels are tak...

A new test, the Moral Judgment Test-PE (MJT-PE), has good validity but scores on Competence should be used with great care. These scores will differ from those of the original Moral Judgment Test (MJT) because the single dilemma is targeted to the specific population of interest, physical educators. This reduces the variance in such a way that scores on the new test cannot be compared with or i...

In this contribution, which is based on the paper [4], we give a constructive description of centrally symmetric equiframed curves, i.e., centrally symmetric closed convex curves that are touched at each of their points by some circumscribed parallelogram of smallest area. Equiframed curves and their higher dimensional analogues were introduced by Pe lczynski and Szarek [7]. This class of curve...