نتایج جستجو برای: phenazine 1 carboxylic acid

تعداد نتایج: 3296523  

Journal: :Applied and environmental microbiology 2012
Dmitri V Mavrodi Olga V Mavrodi James A Parejko Robert F Bonsall Youn-Sig Kwak Timothy C Paulitz Linda S Thomashow David M Weller

Natural antibiotics are thought to function in the defense, fitness, competitiveness, biocontrol activity, communication, and gene regulation of microorganisms. However, the scale and quantitative aspects of antibiotic production in natural settings are poorly understood. We addressed these fundamental questions by assessing the geographic distribution of indigenous phenazine-producing (Phz(+))...

2016
Kaiquan Liu Hongbo Hu Wei Wang Xuehong Zhang

BACKGROUND The biocontrol strain Pseudomonas chlororaphis GP72 isolated from the green pepper rhizosphere synthesizes three antifungal phenazine compounds, 2-Hydroxyphenazine (2-OH-PHZ), 2-hydroxy-phenazine-1-carboxylic acid (2-OH-PCA) and phenazine-1-carboxylic acid (PCA). PCA has been a commercialized antifungal pesticide registered as "Shenqinmycin" in China since 2011. It is found that 2-OH...

2015
Kyle C. Costa Megan Bergkessel Scott Saunders Jonas Korlach Dianne K. Newman

UNLABELLED Diverse bacteria, including several Pseudomonas species, produce a class of redox-active metabolites called phenazines that impact different cell types in nature and disease. Phenazines can affect microbial communities in both positive and negative ways, where their presence is correlated with decreased species richness and diversity. However, little is known about how the concentrat...

2012
Georg Zocher Orwah Saleh Joel B. Heim Dominik A. Herbst Lutz Heide Thilo Stehle

Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto aromatic substrates in biosynthetic pathways of microbial secondary metabolites. Therefore, these enzymes contribute to the chemical diversity of natural products. Prenylation is frequently essential for the pharmacological properties of these metabolites, including their antibiotic and antitumor activities. R...

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