نتایج جستجو برای: phenanthridine

تعداد نتایج: 222  

Journal: :Biological chemistry 2000
G Haider T von Schrader M Füsslein S Blechert T M Kutchan

A facile test system based on the accumulation of benzo[c]phenanthridine alkaloids in Eschscholzia californica cell suspension culture (an indicator of defense gene activation) has been used to analyze a series of synthetic compounds for elicitor-like activity. Of the 200 jasmonic acid and coronatine analogs tested with this system, representative results obtained with 49 of them are presented ...

Journal: :Environmental science & technology 2008
Miriam León Paumen Paul Stol Thomas L Ter Laak Michiel H S Kraak Cornelius A M Van Gestel Wim Admiraal

This study aimed to monitor PAC availability to the oligochaete Lumbriculus variegatus during 28 days of exposure to spiked sediments, in order to obtain reliable chronic effect concentrations for reproduction. Sediment toxicity tests were performed using three pairs of PAC isomers: two homocyclic compounds (anthracene and phenanthrene), two azaarenes (acridine and phenanthridine), and the two ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1995
V K Misra B Honig

A model based on the nonlinear Poisson-Boltzmann equation is used to study the electrostatic contribution to the binding free energy of a simple intercalating ligand, 3,8-diamino-6-phenylphenanthridine, to DNA. We find that the nonlinear Poisson-Boltzmann model accurately describes both the absolute magnitude of the pKa shift of 3,8-diamino-6-phenylphenanthridine observed upon intercalation and...

Journal: :Acta Crystallographica Section E Structure Reports Online 2009

Journal: :Science China-chemistry 2022

Abstract Here, we describe a general and modular strategy for the rapid assembly of benzo[ c ]phenanthridine (BCP) derivatives using homogeneous gold catalysis. Notably, in contrast to traditional methods based on specially preformed substrates that have an inherent preference formation this class compounds with limited flexibility, protocol is achieved via selectively intramolecular cascade di...

Journal: :Organic & biomolecular chemistry 2011
Lauren R Donaldson Stephen Wallace David Haigh E Elizabeth Patton Alison N Hulme

A Heck cyclisation approach is described for the rapid synthesis of a library of natural product-like small molecules, based on the phenanthridine core. The synthesis of a range of substituted benzylamine building blocks and their incorporation into the library is reported, together with a highly selective cis-dihydroxylation protocol that enables access to the target compounds in an efficient ...

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