We were lately so completely taken in by a goodly volume bearing a title something similar to the one now before us, that it was not without some hesitation that we ventured upon the purchase and perusal of Dr. Clark's. We were indeed, somewhat reassured by the modesty of the title page, and the unpretending humbleness of the preface; but we have waxed too wise and sober on our critical Pharos ...

Distributed Hash Tables (DHTs) may suffer from a high lookup latency due to the issue of topology mismatching between the overlay and the physical underlying network. To handle this problem, recently, some researchers use network coordinates (NCs) to construct topology-aware DHTs(e.g. Canary). However, these proposed DHTs still have room to be improved due to the inaccuracy of NCs. To construct...

The availability of a wide range of immunosuppressive therapies has revolutionized the management of patients who have undergone solid organ transplantation (SOT). However, the cost of immunosuppressive drugs remains high. This situation has led to the development of generic equivalents, which are similar in quality, safety, and efficacy to their approved innovator drugs. There are data availab...

The design and performance of the new cold neutron chopper spectrometer (CNCS) at the Spallation Neutron Source in Oak Ridge are described. CNCS is a direct-geometry inelastic time-of-flight spectrometer, designed essentially to cover the same energy and momentum transfer ranges as IN5 at ILL, LET at ISIS, DCS at NIST, TOFTOF at FRM-II, AMATERAS at J-PARC, PHAROS at LANSCE, and NEAT at HZB, at ...

IMPORTANCE Adherence to Mediterranean-type diet (MeDi) may delay onset of Alzheimer and Parkinson diseases. Whether adherence to MeDi affects time to phenoconversion in Huntington disease (HD), a highly penetrant, single-gene disorder, is unknown. OBJECTIVES To determine if MeDi modifies the time to clinical onset of HD (phenoconversion) in premanifest carriers participating in Prospective Hu...