Monitoring the negative effect of drugs is a concept that all healthcare professionals would be aware of as part of their professional responsibility. However since 1968, it has evolved into a structured science called 'Pharmacovigilance'. This review aims to sensitize Caribbean healthcare professionals to the global pharmacovigilance network of the World Health Organization and how their activ...

Pharmacovigilance is the subject that deals with the detection, assessment, understanding, and prevention of adverse effects of drugs, or any other drug-related problems. Ecopharmacovigilance is the science & activity concerning detection, assessment, understanding and prevention of adverse effects or other problems related to the presence of pharmaceuticals in the environment, which affect hum...

Pharmacovigilance is concerned with the detection, assessment, understanding, and prevention of adverse reactions to medicines. It is helpful to prevent undesired harm sustained by the patient due to inappropriate or unsafe use of medicinal agents. As the use of drugs and polypharmacy increase in prevalence, pharmacovigilance gains relevance and momentum. Practice-based research networks have t...

Pharmacovigilance can be defined as a set of practices aiming at the detection, understanding and assessment of risks related to the use of drugs in a population, and the prevention of consequential adverse effects. In a narrower sense, the term refers exclusively to postmarket surveillance. This paper briefly outlines how pharmacovigilance has come to play a central role in the regulation of n...

The efficacy and safety of medicines may be different in children compared to adults. The available documentation at the time of approval is, in general more sparse in children and long term data collection may be needed in order to clarify the safety profile in children and particularly to detect any long-term or delayed toxicities in the developing child. Therefore, there is a need to careful...

BACKGROUND Patients have been allowed to report adverse drug reactions (ADRs) directly to the government in some countries, which would contribute to pharmacovigilance. OBJECTIVE We started a pilot study to determine whether web-based patient ADR reporting would work in Japan. This article aims to describe the characteristics of the patient reporters, and to clarify patient views and experien...

A scientific model to support excellence in pharmacovigilance has been developed from first principles by brainstorming sessions and discussions with experts in the field. The model represents a long-term vision of how pharmacovigilance could be conducted in the future. So far it has been developed without any consideration of constraints such as resources or the need for legislative change. Al...

Title: Improved drug safety through intensive pharmacovigilance in hospitalized pediatric patients Authors: Alan Vazquez-Alvarez ([email protected]) Lorena Brennan-Bourdon ([email protected]) Ana Rincón-Sánchez ([email protected]) Maria Islas-Carbajal ([email protected]) Selene Huerta-Olvera ([email protected]) Version: 2 Date: 25 Nov 2017 Author’s ...

The identification of semantically similar linguistic expressions despite their formal difference is an important task within NLP applications (information retrieval and extraction, terminology structuring...) We propose to detect the semantic relatedness between biomedical terms from the pharmacovigilance area. Two approaches are exploited: semantic distance within structured resources and ter...