نتایج جستجو برای: pharmacological activity
تعداد نتایج: 1190309 فیلتر نتایج به سال:
Theophylline, a methylxanthine compound, is known as an efficient bronchodilatator drug, having also anti-inflammatory and immunomodulatory effects. In order to improve its pharmacological profile and to reduce also the serious side effects that appear at high concentrations, new theophylline derivatives have been synthesized. The new compounds are obtained in two steps by the reaction of 8-sub...
PDRN is a proprietary and registered drug that possesses several activities: tissue repairing, anti-ischemic, and anti-inflammatory. These therapeutic properties suggest its use in regenerative medicine and in diabetic foot ulcers. PDRN holds a mixture of deoxyribonucleotides with molecular weights ranging between 50 and 1,500 KDa, it is derived from a controlled purification and sterilization ...
abstract the purpose of this study is twofold: on the one hand, it is intended to see what kind of noticing-the –gap activity (teacher generated vs. learner generated) is more efficient in teaching l2 grammar in classroom language learning. on the other hand, it is an attempt to determine which approach of the noticing-the-gap- activity is more effective in the long- term retention of grammar...
New diterpenylquinones, combining a diterpene diacid and a naphthoquinone, were prepared from junicedric acid and lapachol. The new derivatives were assessed as gastroprotective agents by the HCl-EtOH-induced gastric lesions model in mice as well as for basal cytotoxicity on the following human cell lines: Normal lung fibroblasts (MRC-5), gastric epithelial adenocarcinoma (AGS), and hepatocellu...
Relevant drawbacks of the molecular structure and mechanism of the action of camptothecins are the instability of the E ring lactone and the reversibility of drug-target interaction. Such features are expected to limit the clinical efficacy of conventional camptothecins. In an attempt to overcome these limitations and to improve the pharmacological profile of camptothecins, a novel series of se...
Novel strategies of antiinflammatory therapy are based upon pharmacological agents capable to enhance the resolution - i.e. the termination of the beneficial inflammation before it may turn into an adverse chronic stage. In contrast to the current therapy, which antagonises the formation of proinflammatory mediators, the "proresolving" therapy promotes natural antiinflammatory processes. It is ...
there is the need for new drugs with better action and lesser side effects. a lot of research is being undertaken to find out new plant drugs, their extraction and pharmacological evaluation. one of such plant is curcuma aromatica whichbelongs to the genus curcuma and reported to have high ethno-botanical values in traditional medicine. the present study evaluates comparative pharmacological ac...
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