نتایج جستجو برای: pharmaceutical tablets
تعداد نتایج: 77375 فیلتر نتایج به سال:
In recent years the growing interest in drug stability problem has been observed. The stability of pharmaceutical products seems to play an important role from the economical point of view. However, there are not many studies that reported about the stability of drugs past their expiration dates. The objective of the current study was to determine tablet content of expired tablets and tablets w...
An ultraviolet spectrophotometric and a nonaqueous volumetric method for determining terbinafine hydrochloride (TH) in pharmaceutical formulations are presented. The UV spectrophotometric procedure was developed for assay of TH in raw materials, tablets, and creams. The method was tested for linearity (0.8-2.8 micrograms/mL, r = 0.9997), recovery (102.00% for creams and 99.90% for tablets) and ...
Background: Starch of sweet potatoes is one the ingredients that has many benefits, including in pharmaceutical field, especially as a excipient formulations. But it poor flow properties. Objective: The objective study to isolate, characterise, modify and formulate starch Purple (I. batatas L.Poir) into tablet dosage forms. Method: purple potato obtained from isolation, then modified improve it...
Abstract Controlled disintegration of pharmaceutical tablets has been interest for consistency checks and drug delivery. Under sonication, tablet is accelerated. This acceleration attributed to the existence microscopic air pockets inside compacted tablets. In this study, we investigated such by subjecting micro-computed tomography. addition, subjected from same batch sonography. The were measu...
The manufacture of bi-layer tablets, produced by the sequential compaction of loose powder layers has recently become of increased interest within the pharmaceutical industry due to the tailored release profiles of active ingredients that may be obtained. In a bi-layer configuration, the immediate release layer of the bilayer tablet has worked as the loading dose and the sustained release layer...
Bi-layer tablet is a new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Bi-layer tablet is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one layer is immediate release as initial dose and second ...
Hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. Today this technology has found its place in the array of pharmaceutical manufacturing operations. Melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...
INTRODUCTION Direct compression is the process of tabletting of a blend of ingredients, the compression mix, without a preliminary granulation or aggregation process. The compression mix contains the active pharmaceutical ingredient blended with one or more excipients.1 It has been estimated that less than 20 percent of pharmaceutical materials can be compressed directly into tablets. The rest ...
The aim of this study was to develop a derivative of chitosan as pharmaceutical excipient used in sustained-release matrix tablets of poorly soluble drugs. A water-soluble quaternary ammonium carboxymethylchitosan was synthesized by a two-step reaction with carboxymethylchitosan (CMCTS), decylalkyl dimethyl ammonium and epichlorohydrin. The elemental analysis showed that the target product with...
There is no approved comparator list in Mongolia. The innovator pharmaceutical product is usually the most logical comparator product for a multisource pharmaceutical product because its quality, safety and efficacy should have been well assessed and documented in premarketing studies and postmarketing monitoring schemes. There are registered 65 products in Mongolia, containing Paracetamol, and...
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