In the environment, pharmaceutical residues are a field of particular interest due to adverse effects either human health or aquatic and soil environment. Because diversity these compounds, at least 3000 substances were identified categorized into 49 different therapeutic classes, several actions urgently required multiple steps, main ones: (i) occurrence studies active compounds (PhACs) in wat...

Background & Aim: Papaver bracteatum Lindl.  (Papaverace) is an important pharmaceutical plant which contains isoqinoline alkaloids. Isoqinoline alkaloids constitute one distinct group of secondary metabolites of the Papaverace family. Codeine and thebaine are important alkaloids of Papaver bracteatum which use widely due to its medicinal properties. Therefore it is...

The advent of robust, rugged, and current Good Manufacturing Practices (cGMP) compliant hand-held Raman spectrometers provides a wealth of opportunities for the analytical pharmaceutical chemist to bring the laboratory to the sample. This paper discusses the use of hand-held Raman spectrometers for the development of qualitative chemical identification methods for a number of well-known pharmac...

Drug screening is the first phase of a drug development process taking 10 to 15 years for detecting potential drug candidates. Screening of candidates on drug targets is a random process and functions of drugs are not known in most trials, therefore traditional drug screening is not efficient and expedite process. In vitro nanomedicine and drug screening platforms provide significant contributi...

Technetium-99m ethyl cysteinate dimer (Tc-99m-ECD) is an essential imaging agent used in evaluating the regional cerebral blood flow in patients with cerebrovascular diseases. Determination of active pharmaceutical ingredient, that is, L-Cysteine, N, N'-1,2-ethanediylbis-, diethyl ester, dihydrochloride (ECD) in ECD Kit is a relevant requirement for the pharmaceutical quality control in process...

The advantages of the therapeutic profile of quetiapine have led to increasing use in the clinical practice, which encourages the development of new analytical method to provide driving force in today’s pharmaceutical industry. Higher sample throughput with more information per sample may decrease the time to market, an important driving force in today’s pharmaceutical industry [1-3]. UPLC is a...

The solid state studies of pharmaceutical ingredients is essential for complete characterization of pharmaceutical products. The pharmaceutical industry utilizes a wide variety of techniques to research, develop, and manufacture compounds which possess high therapeutic value. Thermo microscopy or thermo-optical technique or hot stage microscopy (HSM) is quite extensively used to characterize th...

The aim of this study was to develop and validate a simple, sensitive, precise and cost-effective one-level agar diffusion (5+1) bioassay for estimation of potency and bioactivity of Levofloxacin in pharmaceutical preparation which has not yet been reported in any pharmacopoeia. Among 16 microbial strains, Bacillus pumilus ATCC-14884 was selected as the most significant strain against Levofloxa...

Information plays a vital role in effective management of any system. With the Health Management Information System (HMIS), specific information may be provided to support the decision makers at various levels of the health system to assist evidence-based decision making. It is almost three decades (from 1984) that Iranian Ministry of Health (MoH) has used HMIS in its pharmaceutical sector as a...