For many years, investigators have sought after high-resolution fluorescence imaging in centimeter-deep tissue because many interesting in vivo phenomena-such as the presence of immune system cells, tumor angiogenesis, and metastasis-may be located deep in tissue. Previously, we developed a new imaging technique to achieve high spatial resolution in sub-centimeter deep tissue phantoms named con...

Tissue-mimicking phantoms are widely used for the calibration, evaluation and standardisation of medical imaging systems, and for clinical training. For photoacoustic imaging, tissue-mimicking materials (TMMs) that have tuneable optical and acoustic properties, high stability, and mechanical robustness are highly desired. In this study, gel wax is introduced as a TMM that satisfies these criter...

We are developing a photon-counting spectral CT detector with a small pixel size of [Formula: see text] mm(2), offering a potential advantage for better visualization of small structures in pediatric patients. The purpose of this study is to determine the patient size dependent scanning parameters (kVp and mAs) for pediatric CT in two imaging cases: adipose imaging and iodinated blood imaging. ...

Quality control tests are mandatory and essential to monitor Magnetic Resonance Imaging equipment. These assist in determining improper functioning or parameters below established reference levels. The objective of this study was perform quality magnetic resonance imaging equipment compare their methodology with both FLUKE KONEX phantoms. Different protocols were used for evaluation, including ...

Physical anthropomorphic phantoms have been utilized for a variety of dosimet- ric studies across a range of procedures utilizing diagnostic imaging equipment. Unfortunately, these phantoms are often limited to a single reference size, which often may not be representative of the patient population at large. This work set out to develop an adipose tissue-equivalent substitute material that coul...

We report on a resonant acoustic radiation force optical coherence elastography (ARF-OCE) technique that uses mechanical resonant frequency to characterize and identify tissues of different types. The linear dependency of the resonant frequency on the square root of Young's modulus was validated on silicone phantoms. Both the frequency response spectrum and the 3D imaging results from the agar ...