نتایج جستجو برای: phage vaccine

تعداد نتایج: 127647  

Background and purpose: Despite advances in oral health and dental industry, tooth decay remains one of the most common oral diseases. One of the new methods to combat dental plaque, which is the main cause of caries, is using specific lytic bacteriophage. This study aimed to investigate the effect of isolated specific lytic phage against growth and biofilm inhibition of Streptococcus mutans an...

Journal: :applied biotechnology reports 0
mozafar mohammadi applied biotechnology research center, baqiyatallah university of medical sciences, tehran, iran peyman bemani recombinant antibody laboratory, dept. of immunology, shiraz university of medical sciences, shiraz, iran neda zarei department of biotechnology, school of veterinary medicine, shiraz university, shiraz, iran

phage elisa is a common method to confirm binding of obtained phages from phage display technique to related antigens. enzyme-conjugated antibody directed against the major capsid protein (pviii) or enzyme-conjugated secondary antibody against the primary antibody is used as a detection system in phage elisa. we have suggested to express an acid phosphatase (sapm) enzyme on m13 pix minor coat p...

Journal: :jundishapur journal of microbiology 0
muhsin jamal atta-ur-rahman school of applied biosciences (asab), national university of sciences and technology (nust), islamabad, pakistan; emerging pathogens institute (epi), university of florida (uf), florida, usa; atta -ur-rahman school of applied biosciences (asab), national university of sciences and technology (nust), kashmir highway, sector h-12, islamabad, pakistan. tel: +92-3469398028, fax: +92-5190856102 tahir hussain atta-ur-rahman school of applied biosciences (asab), national university of sciences and technology (nust), islamabad, pakistan chythanya rajanna das emerging pathogens institute (epi), university of florida (uf), florida, usa saadia andleeb atta-ur-rahman school of applied biosciences (asab), national university of sciences and technology (nust), islamabad, pakistan

results the bacteriophage, designated mj1, was isolated by testing against a clinical mdr e. coli 3 strain. the mj1 phage showed a wide range of heat and ph stability. the phage morphology, determined by transmission electron microscopy, revealed a structure comprised of a head (108 ± 0.2 nm long by 128 ± 0.5 nm wide) and a contractile tail (123 ± 0.5 nm long by 15 - 26 nm wide). these features...

Journal: :iranian journal of public health 0
k.badalian f.shariati h.sabetzadeh

a total of 610 strains of shigellae isolated from cases of diarrhea in iran during 1962-73 were studied with respect to their phage type, as well as antibiotic resistance and transferable drug resistance along with serotyping. it was shown that there was some relation between serotypes and phage types but no association could be found between phage types and resistance pattern.

Journal: :Current bioscience 2021

Bacterial molecular mimicry in autoimmune diseases is one of the leading mechanisms by which microorganisms may induce autoimmunity and survive host. The main purpose current study was to determine microbes that elicit reactions through identify most relevant approaches investigate this mechanism. A classic example M protein Streptococcus pyogenes, induces antibody cross-reactivity with a cardi...

2014
Lourena Emanuele Costa Luiz Ricardo Goulart Nathália Cristina de Jesus Pereira Mayara Ingrid Sousa Lima Mariana Costa Duarte Vivian Tamietti Martins Paula Sousa Lage Daniel Menezes-Souza Tatiana Gomes Ribeiro Maria Norma Melo Ana Paula Fernandes Manuel Soto Carlos Alberto Pereira Tavares Miguel Angel Chávez-Fumagalli Eduardo Antonio Ferraz Coelho Mauricio Martins Rodrigues

BACKGROUND The development of cost-effective prophylactic strategies to prevent leishmaniasis has become a high-priority. The present study has used the phage display technology to identify new immunogens, which were evaluated as vaccines in the murine model of visceral leishmaniasis (VL). Epitope-based immunogens, represented by phage-fused peptides that mimic Leishmania infantum antigens, wer...

2017
Ching Hoong Chew Yvonne Ai Lian Lim Kek Heng Chua

BACKGROUND Plasmodium is an obligate intracellular parasite. Apical membrane antigen 1 (AMA1) is the most prominent and well characterized malarial surface antigen that is essential for parasite-host cell invasion, i.e., for sporozoite to invade and replicate within hepatocytes in the liver stage and merozoite to penetrate and replicate within erythrocytes in the blood stage. AMA1 has long serv...

A. S. Srujana D. S. Akhila, J. Sonalika K. S. Santhosh M. R. Juliet

Background: Salmonella, a bacterial genus of more than 2500 serotypes is considered as the most significant foodborne pathogen causing infections in humans and animals. Increased antimicrobial resistance and persistence of antimicrobial residues in food matrices warrants the need for alternative infection management strategies. Aims: The present study aimed to isolate and evaluate the lytic act...

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