An acid tolerance response (ATR) has been demonstrated in Listeria monocytogenes and Salmonella enterica serovar Typhimurium in response to low pH poised (i.e., adapted) with acetic or lactic acids at 20 degrees C and modeled by using dynamic differential equations. The ATR was not immediate or prolonged, and optimization occurred after exposure of L. monocytogenes for 3 h at pH 5.5 poised with...

The polyplexes formed by nucleic acids and polycations have received a great attention owing to their potential application in gene therapy. In our study, we report experimental results and modeling outcomes regarding the optimization of polyplex formation between the double-stranded DNA (dsDNA) and poly(ʟ-Lysine) (PLL). The quantification of the binding efficiency during polyplex formation was...

The objective of the present investigation was to reduce the bitterness of artemether (ARM). Microparticles were prepared by the coacervation method using Eudragit E 100 (EE) as polymer and sodium hydroxide solution as nonsolvent for the polymer. A 32 full factorial design was used for optimization wherein the amount of drug (A) and polymer (B) were selected as independent variables and the bit...

The Present study summarizes the biosynthesis, characterization and optimization of auxins by Piriformospora indica and its effect on the growth of Solanum melongena L. cultivars. The biosynthesis of auxins was greatly influenced by the addition of tryptophan. Based on the data obtained from traditional one factor at a time method, optimization was carried out using the response surface methodo...

Distillery industry is recognized as one of the most polluting industries in India with a large amount of annual effluent production. In this present study, the optimization of electrochemical treatment process variables was reported to treat the color and COD of distillery spent wash using Ti/Pt as an anode in a batch mode. Process variables such as pH, current density, electrolysis time, and ...

Bioremediation of phenol was done using Candida tropicalis SSK01 immobilized cells isolated from petroleum contaminated soil. Optimization of phenol degradation studies was carried at 30 °C to 40 °C, pH 6 to 8 and initial concentration of 300 mgl⁻¹ to 900 mgl⁻¹. Candida tropicalis SSK01 cells immobilized using sodium alginate were used in phenol degradation studies. Optimization of phenol degra...

pH variation in sewers has a significant effect on hydrogen sulfide production and emissions, and hence its accurate prediction is critical for the optimization of mitigation strategies. In this study, the nature and dynamics of pH variation in a sewer system is examined. Three sewer systems collecting domestic wastewater were monitored, with pH in all cases showing large diurnal variations. pH...

We present a decision support system for the fermentation step in winemaking based on a mathematical model of kinetics of alcoholic fermentation. We used an optimization technique in order to predict the fermentation step. This optimization technique was carried out using the method of factorial analysis. The first interesting application of this system, rather than existing ones, comes from th...

AIMS A major problem in industrial fermentation of organic acids with micro-organisms is to ensure a suitable pH in the culture broth. To circumvent this problem, we investigated the effect of citrate, which is a widely used auxiliary energy co-substrate, on cell growth, organic acid production and pH homeostasis among extracellular environment, cytoplasm and vacuole, in the pyruvic acid produc...

OBJECTIVES This study highlights xylanase overproduction from Bacillus mojavensis via UV mutagenesis and optimization of the production process. MATERIALS AND METHODS Bacillus mojavenis PTCC 1723 underwent UV radiation. Mutants' primary screening was based on the enhanced Hollow Zone Diameter/ Colony Diameter Ration (H/C ratios) of the colonies in comparison with the wild strain on Xylan agar...