Organophosphorus pesticide poisoning causes tens of thousands of deaths each year across the world. Poisoning includes acute cholinergic crisis as a result of AChE inhibition, intermediate syndrome (IMS) due to neuromuscular necrosis and organophosphate-induced delayed neuropathy (OPIDN) due to inhibition of neuropathy target esterase (NTE). Standard treatment for acute poisoning involves admin...

Data concerning clinical cases of pesticide poisoning from 1998 to 2002 from the hospitals affiliated with the Japanese Association of Rural Medicine were analyzed. 346 cases of poisoning by agricultural chemicals were reported from 65 hospitals. Suicides accounted for 70% of pesticide poisoning cases, followed by accidental exposures during spraying work (16%) and accidental ingestion (8%). Th...

Organophosphorus (OP) pesticide poisoning is a significant problem worldwide. Research into new antidotes for these acetylcholinesterase inhibitors, and even optimal doses for current therapies, is hindered by a lack of standardized animal models. In this study, we sought to characterize the effects of the OP pesticide parathion on acetylcholinesterase in a Wistar rat model that included compre...

background: organophosphorus (op) poisoning is a major public health problem in developing world. op pesticides inhibit carboxylic esterase enzymes including plasma cholinesterase (pche). clinical manifestations following op poisoning can be associated with the extent of decrease of pche. this study was designed to investigate the relevance of pche level to clinical manifestations in op poisoni...

We examined the causes and mortality of poisoning in the province of Mazandaran. In all, 1751 poisoning cases referred to four main hospitals over a three-year period (1997-2000) were included. More poisoning cases were females (55.5%) than males (45.5%) but the proportional mortality for males was greater than for females (65% versus 35%). The greatest proportion of poisonings occurred between...

The ever increasing demand for more food production has been met by adoption of better crop protection measures. Since world war II synthetic chemicals/poisons have been extensively used for the control of agricultural as well as household and medical insect pests. These poisons which otherwise are employed for human benefit can also be called as economic poisons. Pesticides used for the contro...

background: identification of regional pattern of poisoning is essential for health care authorities for proper planning on prevention programs and optimized management of antidote stockpiles. this study was designed to evaluate one-year epidemiologic pattern of acute poisoning cases treated at a tertiary care hospital in thrissur, india. methods: in this retrospective cross sectional study, me...

There are potentially many situations in which creatures will be subject to infrequent but regular culling. In terms of controlling crop pests, some farmers may only be able to afford to apply pesticides occasionally. Alternatively, pesticides may be applied only occasionally to limit their unwelcome side effects, which include pesticide resistance, chemical poisoning of agricultural workers, a...

AIMS OF THE STUDY To report the clinical features, laboratory findings and the management instituted for the patients with acute Amitraz Poisoning. METHODS AND MATERIAL Three cases of acute Amitraz Intoxication were studied and compared with previous reports from the literature. RESULTS All the three female cases were brought to our hospital with age ranging from 2 years to 40 years, consum...