نتایج جستجو برای: persistent pulmonary hypertension of the newborn

تعداد نتایج: 22848984  

2011
Christina Luong Yves Sauve Debby Koonen Kathryn G. Todd

Background—Lung hypoplasia and persistent pulmonary hypertension of the newborn limit survival in congenital diaphragmatic hernia (CDH). Unlike other diseases resulting in persistent pulmonary hypertension of the newborn, infants with CDH are refractory to inhaled nitric oxide (NO). Nitric oxide mediates pulmonary vasodilatation at birth in part via cyclic GMP production. Phosphodiesterase type...

Journal: :Circulation 2011
Christina Luong Juliana Rey-Perra Arul Vadivel Greg Gilmour Yves Sauve Debby Koonen Don Walker Kathryn G Todd Pierre Gressens Zamaneh Kassiri Khurram Nadeem Beverly Morgan Farah Eaton Jason R Dyck Stephen L Archer Bernard Thébaud

BACKGROUND Lung hypoplasia and persistent pulmonary hypertension of the newborn limit survival in congenital diaphragmatic hernia (CDH). Unlike other diseases resulting in persistent pulmonary hypertension of the newborn, infants with CDH are refractory to inhaled nitric oxide (NO). Nitric oxide mediates pulmonary vasodilatation at birth in part via cyclic GMP production. Phosphodiesterase type...

Journal: :Pediatrics 1990
Perraju Bendapudi Gopinath Gangadhara Rao Anne Greenough

Persistent pulmonary hypertension of new born (PPHN) is associated with mortality and morbidity; it may be idiopathic or secondary to a number of conditions. The mainstay of diagnosis and to exclude structural abnormalities is echocardiography. Brain type natriuretic peptide (BNP) levels are elevated in PPHN, but are insufficiently sensitive to contribute to routine diagnosis. Management includ...

Journal: :Archives of disease in childhood 1991
Y K Abu-Osba

OBJECTIVE: To review the medical literature, emphasizing the new scientific advances in the treatment of persistent pulmonary hypertension of the newborn. SOURCES: Literature review using Medline and Cochrane library. SUMMARY OF THE FINDINGS: Persistent pulmonary hypertension of the newborn (PPHN) is characterized by an increase in pulmonary vascular resistance associated with right to left shu...

Journal: :Archives of disease in childhood. Fetal and neonatal edition 1999
S Kusuda N Shishida N Miyagi M Hirabayashi T J Kim

AIM To determine if the haemodynamics of systemic and cerebral circulation are changed during treatment for persistent pulmonary hypertension of the newborn (PPHN). METHODS Fifteen term newborn piglets with hypoxia induced pulmonary hypertension were randomly assigned either tolazoline infusion (Tz), hyperventilation alkalosis(HAT), and inhaled nitric oxide (iNO). Mean pulmonary arterial pres...

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