نتایج جستجو برای: permeation enhancers

تعداد نتایج: 15318  

Journal: :Journal of photochemistry and photobiology. B, Biology 2006
Andrzej Bugaj Asta Juzeniene Petras Juzenas Vladimir Iani Li Wei Ma Johan Moan

The influence of skin permeation enhancers, such as dimethyl sulphoxide (DMSO) and 1-[2-(decylthio)ethyl]azacyclopentan-2-one (HPE-101), Labrafac CC, Labrafil, Labrasol and Transcutol in a concentration of 10% (wt./wt.) on the formation of porphyrins in normal mouse skin from topical application of creams with methyl 5-aminolevulinate (MAL) was studied. The concentration of porphyrins in the mo...

Journal: :Journal of oleo science 2013
Xin Liu Teng Chen Xuesong Liu Yong Chen Longhu Wang

The present study investigated the feasibility of ostrich oil utilizing as a promising vehicle for improved skin permeation of sinomenine with reference to vaseline matrix containing different content of chemical enhancers. The fatty acid composition of ostrich oil was analyzed by GC-MS. Penetration enhancing potential of ostrich oil on permeation of sinomenine across rat abdominal skin in vitr...

Journal: :Skin pharmacology and physiology 2010
W J Romonchuk

Dermal permeation through human epidermis and uptake into isolated human stratum corneum (SC) that was and was not delipidized were measured for 2 model compounds, 4-cyanophenol (CP) and methyl paraben (MP), from saturated aqueous solutions containing 1 or both compounds. Because the solutions were in equilibrium with the pure CP and MP, the thermodynamic activity of the compounds was constant....

2009
MALAY K. DAS ABDUL B. AHMED Malay K. Das Abdul B. Ahmed

The enhancing effect of ascorbic acid and triethyl citrate (TEC) on the in vitro skin permeation of rofecoxib across rat epidermis was investigated. Skin pre-treatment with ascorbic acid and TEC at different concentrations, followed by application of rofecoxib gel, showed higher permeation flux than the control condition. The mechanism underlying this permeation enhancement was probed with four...

Journal: :jundishapur journal of natural pharmaceutical products 0
maryam kouchak department of pharmaceutics, faculty of pharmacy, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; nanotechnology research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran somayeh handali nanotechnology research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; nanotechnology research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-91611479987, fax: +98-6113738381

background: cellulite is the accumulation of subcutaneous fat and connective tissue in tights and buttocks. xanthines, such as aminophylline, are used as phosphodiesterase inhibitors, and are also adenosine receptor antagonists. objectives: the aim of the present study was to characterize in vitro aminophylline transdermal absorption through shed snake skin, and to investigate the absorption en...

Journal: :research in pharmaceutical sciences 0
j shokri sh azarmi z fasihi s hallaj-nezhadi a nokhodchi y javadzadeh

a suitable emulgel formulation of piroxicam was prepared and its percutaneous permeation was investigated using wistar rat skin and diffusion cell technique. the concentrations of the drug in receptor phase of diffusion cells were measured using hplc method. the effect of three types of penetration enhancers (myrj 52, cineol and transcutol p) with different concentrations on transdermal permeat...

Journal: :International Journal of Innovations in Biological and Chemical Sciences 2016

Asal Mirmohammad Sadeghi Mohammad Reza Avadi Morvarid Goharzadeh Orkide Ghorban Dadras Zahra Ghassemi

In the past decade, many strategies have been developed to enhance oral drug delivery. Different techniques were investigated, amongst those the use of permeation enhancers such surfactants and biodegradable polymers were studied more extensively. Chitosan and its derivatives have been studied as permeation enhancer. The aim of the current study was to develop a nanoparticulate system based on ...

Afshin Zarghi, B Shahmir H Moghimi

Curcumin is the active component of Curcuma species including C. longa (turmeric). This molecule is well known for its anti-inflammatory effect, which seems to be stronger than that of hydrocortisone. Curcuma species have been used in Asian traditional medicine as topical anti-inflammatory drugs. Curcumin has poor oral bioavailability and its topical application could be of choice, particularly...

Assal Mir Mohammad Sadeghi Mohammad Reza Avadi Morvarid Goharzadeh Orkide Ghorban Dadras

In the past decade, many strategies have been developed to enhance oral drug delivery. Different techniques were investigated, amongst those the use of permeation enhancers such surfactants and biodegradable polymers were studied more extensively. Chitosan derivatives have been studied as permeation enhancer in free soluble form and as nanoparticulate systems. The aim of the current work wa...

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