PERHAPS THERE IS NO major pathological state so profound in its damaging effects on the sufferer, on his family, and on society as the brain injury produced by cardiac arrest, ischemic stroke, or other anoxic states. Thus, there is great interest among physicians and the lay public in experimental results which suggest a protective effect against brain damage after either focal or global brain ...

PERHAPS THERE IS NO major pathological state so profound in its damaging effects on the sufferer, on his family, and on society as the brain injury produced by cardiac arrest, ischemic stroke, or other anoxic states. Thus, there is great interest among physicians and the lay public in experimental results which suggest a protective effect against brain damage after either focal or global brain ...

background myocardial injury caused by ischemia-reperfusion leads to cardiac dysfunction, tissue injury and metabolic changes. the production of reactive oxygen species (ros) and lipid peroxidation are accompanied by ischemia-reperfusion injury. objectives the aim of this study was to assess the cardio protective potential effects of crocin in comparison with vitamin e on antioxidant capacity i...

Objective(s) In this study, effects of chronic administration of oral natural honey against ischemia/reperfusion (I/R)-  induced cardiac arrhythmias were investigated in isolated rat heart. Materials and Methods Male Wistar rats were divided into four groups (n= 10-14 rats in each group) and fed with natural honey (1%, 2% and 4% dissolved in the drinking water) for 45 days except for the con...

In the current study, effects of acute short term administration of fructose on cardiac arrhythmias and myocardial infarction size following ischemia/reperfusion were investigated in isolated rat heart. The hearts were subjected to 30 min zero flow global ischemia followed by 120 min reperfusion. In the control group, the hearts were perfused by normal drug free Krebs-Henseleit (K/H) solution t...

Objective(s) This study aimed to examine whether acetyl-L-carnitine (ALC) was able to reduce cardiac arrhythmias and infarct size in the ischemic-reperfused isolated rat heart. Materials and Methods The isolated hearts were mounted on a Langendorff apparatus then perfused by a modified Krebs-Henseleit solution during 30 min regional ischemia and 120 min reperfusion (control) or by enriched K...

bipolar cardiac electrograms were obtained in dogs from ischemic areas following temporary coronary artery ligation. characteristic alterations from the controls were observed, including increase in dura tion, decrease in amplitude and alterations in configuration. these changes were found to be completely reversible upon restoration of coronary flow. the bipolar electrogram has been recommende...

Ischemia-induced stroke is the most common disease of the nervous system and is associated with a high mortality rate worldwide. Cerebral ischemia may lead to remote organ dysfunction, particular in the lungs, resulting in lung injury. Nowadays, bone marrow-derived mesenchymal stem cells (BMSCs) are widely studied in clinical trials as they may provide an effective solution to the treatment of ...